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Image Unavailable-ABCAAB184787-100

Anti-Caspase-3 Rabbit Monoclonal Antibody [clone: EPR18297]

Katalogové číslo: (ABCAAB184787-100)
Dodavatel: Abcam
Popis: Anti-Caspase-3 Rabbit Monoclonal Antibody [clone: EPR18297]
Měrná jednotka: 1 * 100 µl
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Peripheral IV cannulae, Venflon™ Pro

Dodavatel: BD Medical
Popis: Peripheral IV cannulae with injection port and obturator.

Product Image-114-7831

ESD safety ankle boots, lace-up, Dimension Pro, Horizon Mid

Dodavatel: ELTEN
Popis: Leather-free anti-slip ESD safety shoes made from hydrophobised microfibre and hydrophobised textile Cordura® (tear and abrasion resistant, dirt and water repellent) upper, a full padded bellows tongue and a slip resistant dual-density TPU/PU sole Dimension Pro.

Environmentally Preferable

Product Image-50-9882-T025

Anti-LRRC32 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: GARP5]

Dodavatel: Tonbo Biosciences
Popis: The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cytokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells.

Image Unavailable-BOSSBS-3228R

Anti-IKBKG Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-3228R)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13393R-HRP

Anti-EPRS Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-13393R-HRP)
Dodavatel: Bioss
Popis: The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. ProRS (Prolyl-tRNA synthetase), also known as EPRS, EARS, PARS, QARS, QPRS, PIG32 or GLUPRORS, is a 1,512 amino acid protein that contains three WHEP-TRS domains and belongs to both the class-I and class-II aminoacyl-tRNA synthetase family. Functioning as a component of the multisynthase complex, ProRS uses ATP to catalyze the conversion of L-glutamate and tRNA(Glu) to L-glutamyl-tRNA(Glu), as well as the conversion of L-proline and tRNA(Pro) to L-prolyl-tRNA(Pro).
Měrná jednotka: 1 * 100 µl
Image Unavailable-PRSI91-089

Human Recombinant BID (from E. coli)

Katalogové číslo: (PRSI91-089)
Dodavatel: ProSci Inc.
Popis: BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.
Měrná jednotka: 1 * 0,05 mg

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Image Unavailable-BOSSBS-5760R-A680

Anti-FAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-5760R-A680)
Dodavatel: Bioss
Popis: Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).
Měrná jednotka: 1 * 100 µl
Image Unavailable-USBIL2525-28B

Anti-LBP Mouse Monoclonal Antibody [clone: 9G216]

Katalogové číslo: (USBIL2525-28B)
Dodavatel: US Biological
Popis: Anti-LBP Mouse Monoclonal Antibody [clone: 9G216]
Měrná jednotka: 1 * 100 µG
Product Image-8181-96

Destičky k precipitaci proteinu J.T.Baker® Bakerbond®

Dodavatel: Avantor
Popis: Destičky k precipitaci proteinu J.T.Baker® Bakerbond® umožňují rychlé odstranění proteinů z biologických vzorků.

Image Unavailable-USBIN2108-75B

Anti-NRG1 Rabbit Polyclonal Antibody

Katalogové číslo: (USBIN2108-75B)
Dodavatel: US Biological
Popis: Anti-NRG1 Rabbit Polyclonal Antibody
Měrná jednotka: 1 * 50 µG
Image Unavailable-BOSSBS-1346R-A555

Anti-TRP73 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-1346R-A555)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-A750

Anti-Tp73 Protein Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-1346R-A750)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-A350

Anti-TRP73 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-1346R-A350)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-FITC

Anti-TRP73 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-1346R-FITC)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13671R-A680

Anti-TAX1BP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-13671R-A680)
Dodavatel: Bioss
Popis: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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