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Kyselina vanilinová, Sigma-Aldrich®

Dodavatel: Merck

Popis: Kyselina vanilinová, Sigma-Aldrich®

6-O-Palmitoyl-L-ascorbic acid ≥95.0% NF

Dodavatel: Spectrum Chemical

Popis: Ascorbyl Palmitate, NF is often used to promote flow of tableting powders and to prevent their sticking in tablet presses.

Letermovir 98%

Katalogové číslo: (472721000.)

Dodavatel: Thermo Fisher Scientific

Popis: Letermovir 98%

Měrná jednotka: 1 * 100 mg

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Anti-ATXN7 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-11318R-A647)

Dodavatel: Bioss

Popis: The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).

Měrná jednotka: 1 * 100 µl

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Anti-ATXN7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-11318R-A350)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

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Anti-RNF21 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-9244R-HRP)

Dodavatel: Bioss

Popis: Tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein 1 (IFP1), is a 488 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Three isoforms of TRIM34 exist as a result of alternative splicing events. Isoform 1, the most abundant isoform, is highly expressed in placenta, spleen, colon and peripheral blood leukocytes. Studies have shown that Interferon (IFN) stimulation leads to an upregulation of TRIM34. These findings suggest that TRIM34 maybe a downstream effector that mediates IFN activities.

Měrná jednotka: 1 * 100 µl

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