Hledali jste: β-Nicotinamide adenine dinucleotide (NAD, oxidized form)

Dodavatel: PanReac AppliChem

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma)

Dodavatel: Thermo Scientific

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma) 97%

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Dodavatel: MP Biomedicals

Popis: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.

Dodavatel: MP Biomedicals

Popis: This grade of NAD is intended for applications where maximum reagent purity is not critical. Well suited for use on most automatic analysers.

Dodavatel: MP Biomedicals

Popis: Major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins. Recently reported to be a P2Y11 agonist.

Katalogové číslo: (SIALN8535-15VL)

Dodavatel: Merck

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma), Sigma-Aldrich®

Měrná jednotka: 1 * 15 Vial

Akce

Katalogové číslo: (SIALN8410-15VL)

Dodavatel: Merck

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma), Sigma-Aldrich®

Měrná jednotka: 1 * 15 Vial

Akce

Katalogové číslo: (SIALN8285-15VL)

Dodavatel: Merck

Popis: Nikotinamid-adenindinukleotid (oxidovaná forma), Sigma-Aldrich®

Měrná jednotka: 1 * 15 Vial

Akce