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Image Unavailable-ENZOALX270400M005

SU 9516 ≥95% (by HPLC)

Popis: Cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A (IC50=22nM), CDK1/cyclin B (IC50=40nM) and CDK4/cyclin D1 (IC50=200nM). Has no effect on the activity of PKC, p38, PDGFRβ and EGFR (IC50>10µM). Displays anti-proliferative and pro-apoptotic properties in tumor cells. Inhibits proliferation of growth factor-stimulated colon carcinoma cells by binding to CDK2 and thus preventing the phosphorylation of pRb and its dissociation from E2F.
Katalogové číslo: ENZOALX270400M005
Měrná jednotka: 1 * 5 mg
Dodavatel: ENZO LIFE SCIENCES

New Product


Image Unavailable-APOSBIP1062-100MG

alpha-Maleinimido-omega-carboxysuccinimidyl ester poly(ethyleneglycol), M.W. Mal-PEG-COO-Su 3,000 daltons

Popis: alpha-Maleinimido-omega-carboxysuccinimidyl ester poly(ethyleneglycol), M.W. Mal-PEG-COO-Su 3,000 daltons
Katalogové číslo: APOSBIP1062-100MG
Měrná jednotka: 1 * 100 mg
Dodavatel: Apollo Scientific
Product Image-LIOF9129

Antibiotic assay discs

Popis: Antibiotic Tests, Sulbactam Su 20 µg
Katalogové číslo: LIOF9129
Měrná jednotka: 1 * 250 KS
Dodavatel: LIOFILCHEM
Product Image-ACRO462640010

Sunitinib malate

Popis: Sunitinib malate
Katalogové číslo: ACRO462640010
Měrná jednotka: 1 * 1 g
Dodavatel: Thermo Fisher Scientific
Image Unavailable-METOTWS3036SU304S

TableWorx Performance Work Tables, 304 Stainless Steel Work Surface

Popis: TableWorx is a truly modular platform of performance work tables designed to allow you to customise your perfect solution.
Katalogové číslo: METOTWS3036SU304S
Měrná jednotka: 1 * 1 KS
Dodavatel: Metro International

New Product


Image Unavailable-APOSBIP1165-500MG

alpha-Methoxy-omega-carboxysuccinimidyl ester PEG, M.W. PEG molecular weight 5,000 daltons

Popis: alpha-Methoxy-omega-carboxysuccinimidyl ester PEG, M.W. PEG molecular weight 5,000 daltons
Katalogové číslo: APOSBIP1165-500MG
Měrná jednotka: 1 * 500 mg
Dodavatel: Apollo Scientific
Image Unavailable-BOSSBS-8170R-A680

Anti-NSD1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localised, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
Katalogové číslo: BOSSBS-8170R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Product Image-142-0180

VWR® LED and LCD Ultrasonic Cleaning Baths

Popis: The housing and tank are constructed from high-quality SUS 304 stainless steel, providing durability and longevity. Equipped with user-friendly interface display which offers intuitive function selection and real-time parameter setting. Units also feature intelligent detection on startup, promptly alerting users to any potential issues via buzzer and alarm. Additionally, they continuously monitor the power supply voltage in real-time to ensure optimal operating conditions. The automatic heating stirring function ensures uniform liquid temperature throughout the tank. The anti-leakage tray prevents damage to electrical components and avoids the risk of hazard in case of leakage.
Katalogové číslo: 142-0180
Měrná jednotka: 1 * 1 KS
Dodavatel: VWR Collection

New Product


Image Unavailable-BOSSBS-2080R

Anti-Cecropin Rabbit Polyclonal Antibody

Popis: Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B.
Katalogové číslo: BOSSBS-2080R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Product Image-BOSSBS-8170R

Anti-NSD1 Rabbit Polyclonal Antibody

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Katalogové číslo: BOSSBS-8170R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-8170R-A750

Anti-NSD1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localised, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
Katalogové číslo: BOSSBS-8170R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-8170R-HRP

Anti-NSD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Katalogové číslo: BOSSBS-8170R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-8170R-A350

Anti-NSD1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Katalogové číslo: BOSSBS-8170R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-2962R-HRP

Anti-ERVW-1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Popis: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904). Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein. The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of membranes.
Katalogové číslo: BOSSBS-2962R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-8170R-CY3

Anti-NSD1 Rabbit Polyclonal Antibody (Cy3®)

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Katalogové číslo: BOSSBS-8170R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-8170R-CY7

Anti-NSD1 Rabbit Polyclonal Antibody (Cy7®)

Popis: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Katalogové číslo: BOSSBS-8170R-CY7
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
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