Hledali jste: D-erythro-Sphingosine

Katalogové číslo: (ENZOALX306011M025)

Dodavatel: ENZO LIFE SCIENCES

Popis: PKC inhibitor

Měrná jednotka: 1 * 25 mg

New Product Akce

Katalogové číslo: (ENZOBMLEI1550100)

Dodavatel: ENZO LIFE SCIENCES

Popis: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

Měrná jednotka: 1 * 100 mg

New Product Akce

Dodavatel: Thermo Scientific

Popis: Appearance: White to cream Powder or waxy solid

Bezpečnostní list

Katalogové číslo: (J63584.MB)

Dodavatel: Thermo Scientific

Popis: D-erythro-Sphingosine is used to inhibit protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.

Měrná jednotka: 1 * 25 mg

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