Hledali jste: Aspirin-acyl-\u03B2-D-glucuronide

Katalogové číslo: (PRSI29-650)

Dodavatel: ProSci Inc.

Popis: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BOSSBS-0657R-FITC)

Dodavatel: Bioss

Popis: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0657R-CY5.5)

Dodavatel: Bioss

Popis: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4225R-HRP)

Dodavatel: Bioss

Popis: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4225R-A647)

Dodavatel: Bioss

Popis: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4225R-FITC)

Dodavatel: Bioss

Popis: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4225R-A488)

Dodavatel: Bioss

Popis: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12951R-CY5)

Dodavatel: Bioss

Popis: AASDH is an Acyl CoA synthetase. Acyl CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA .

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIA0747)

Dodavatel: US Biological

Popis: Anti-ACSL1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: ENZO LIFE SCIENCES

Popis: Acyl-CoA synthetase inhibitor

Katalogové číslo: (ABCAAB254958-100)

Dodavatel: Abcam

Popis: Anti-acyl-CoA Thioesterase 2 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7950R-A647)

Dodavatel: Bioss

Popis: ACBD4 is a member of the acyl-coenzyme A binding domain containing protein family. ACBD4 contains 1 ACB (acyl-CoA-binding) domain. There are three isoforms. Its function is unknown.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13497R-A647)

Dodavatel: Bioss

Popis: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13497R-FITC)

Dodavatel: Bioss

Popis: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Apollo Scientific

Popis: Increases leaving group ability of halogens; can be used for conversion of alkyl halides to triflates & acyl halides to acyl triflates; soluble in ether and other organic solvents.

Katalogové číslo: (BOSSBS-5031R-CY3)

Dodavatel: Bioss

Popis: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A Thioesterase 8, also known as ACOT8 may mediate Nef-induced down-regulation of CD4. It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation.

Měrná jednotka: 1 * 100 µl

Akce