Hledali jste: Tonbo Biosciences

Katalogové číslo: (72-8112-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Human IgG + IgA + IgM - Affinity Pure, HRP Conjugate

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (35-8054-U500)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Mouse IgG (H&L), F(ab')2 Fragment - Affinity Pure, FITC Conjugate

Měrná jednotka: 1 * 0,5 mg

Akce

Katalogové číslo: (72-8094-M001)

Dodavatel: Tonbo Biosciences

Popis: Donkey anti-Sheep IgG (H&L) - Affinity Pure, HRP Conjugate

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (35-8064-M002)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Mouse IgM (H&L) - Affinity Pure, FITC Conjugate

Měrná jednotka: 1 * 2 mg

Akce

Katalogové číslo: (70-8037-U500)

Dodavatel: Tonbo Biosciences

Popis: Donkey anti-Rabbit IgG (H&L), F(ab')2 Fragment- Affinity Pure, min x w/ Bovine, Chicken, Goat, Guinea Pig, Hamster, Horse, Human, Mouse, Rat or Sheep

Měrná jednotka: 1 * 0,5 mg

Akce

Katalogové číslo: (35-8081-M002)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Chicken IgY (H&L) - Affinity Pure, FITC Conjugate

Měrná jednotka: 1 * 2 mg

Akce

Dodavatel: Tonbo Biosciences

Popis: The Mouse Dendritic Cell backbone panel is a six-color combination of anti-mouse antibodies. This panel can serve as a backbone for identifying major dendritic cell (DC) subsets (Duriancik DM and Hoag KA. 2009. Cytometry. 75A: 951-959). Hosts: Rat, Armenian Hamster

Dodavatel: Tonbo Biosciences

Popis: The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.

Dodavatel: Tonbo Biosciences

Popis: The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB. The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.

Dodavatel: Tonbo Biosciences

Popis: The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation. The 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.

Katalogové číslo: (72-8111-M001)

Dodavatel: Tonbo Biosciences

Popis: Goat anti-Guinea Pig IgG (H&L) - Affinity Pure, HRP Conjugate

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (72-8076-M001)

Dodavatel: Tonbo Biosciences

Popis: Rabbit anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate

Měrná jednotka: 1 * 1 mg

Akce

Dodavatel: Tonbo Biosciences

Popis: The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).

Dodavatel: Tonbo Biosciences

Popis: The L17F12 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is a member of the scavenger receptor superfamily and is present on approximately 70% of normal peripheral blood lymphocytes. CD5 is involved in modulating antigen receptor signaling in both T and B cells and acts through binding of CD72, its receptor expressed on B cells.

Dodavatel: Tonbo Biosciences

Popis: The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells

Dodavatel: Tonbo Biosciences

Popis: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.