Hledali jste: Shenandoah Biotechnology

Dodavatel: Shenandoah Biotechnology

Popis: Fibroblast growth factor 4 (FGF-4) is a secreted growth factor that is predominantly expressed during bone morphogenesis and embryonic limb development. FGF-4 is an important growth regulator for stem cells, fibroblasts, and endothelial cells. FGF-4 contains a single N-linked glycosylation signal. In-vitro studies suggest that unglycosylated FGF-4 is cleaved into 13 kDa and 15 kDa truncated proteins that have greater biological activity than the wild type 19 kDa FGF-4 protein. Human FGF-4 shares high homology and is cross-reactive with mouse FGF-4. 

Dodavatel: Shenandoah Biotechnology

Popis: Fibroblast growth factor 4 (FGF-4) is a secreted growth factor that is predominantly expressed during bone morphogenesis and embryonic limb development. FGF-4 is an important growth regulator for stem cells, fibroblasts, and endothelial cells. FGF-4 contains a single N-linked glycosylation signal. In-vitro studies suggest that unglycosylated FGF-4 is cleaved into 13 kDa and 15 kDa truncated proteins that have greater biological activity than the wild type 19 kDa FGF-4 protein. Human FGF-4 shares high homology and is cross-reactive with mouse FGF-4. 

Dodavatel: Shenandoah Biotechnology

Popis: Chemerin is a chemoattractant adipokine that is expressed in white adipose, liver, skin, and lung tissues. Chemerin is a ligand for the G protein-coupled receptor chemokine-like receptor 1 (ChemR23), which is expressed on dendritic cells, macrophages, and adipocytes.

Dodavatel: Shenandoah Biotechnology

Popis: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS).

Dodavatel: Shenandoah Biotechnology

Popis: Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3).

Dodavatel: Shenandoah Biotechnology

Popis: Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.

Dodavatel: Shenandoah Biotechnology

Popis: Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells; however, mouse M-CSF shows no activity on human cells.

Bezpečnostní list

Dodavatel: Shenandoah Biotechnology

Popis: Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3).

Dodavatel: Shenandoah Biotechnology

Popis: Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs).  IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter.

Dodavatel: Shenandoah Biotechnology

Popis: Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.

Dodavatel: Shenandoah Biotechnology

Popis: Growth regulated protein gamma (GRO-ɣ), also called CXCL3, acts through the chemokine receptor CXCR2 to promote monocyte migration and adhesion. GRO-ɣ also induces the migration of cerebellar granule neuron precursor cells. 

Katalogové číslo: (SHBT91130)

Dodavatel: Shenandoah Biotechnology

Popis: PRIME-XV TUMORSPHERE SFM 1 * 100 mL

Měrná jednotka: 1 * 100 mL

New Product Akce

Katalogové číslo: (SHBT91139-100ML)

Dodavatel: Shenandoah Biotechnology

Popis: PRIME-XV FREEZIS 1 * 100 mL

Měrná jednotka: 1 * 100 mL

New Product Akce

Katalogové číslo: (SHBT91215)

Dodavatel: Shenandoah Biotechnology

Popis: PRIME-XV NK CELL CDM 1 * 1 L

Měrná jednotka: 1 * 1 L

New Product Akce

Katalogové číslo: (SHBT91149-250ML)

Dodavatel: Shenandoah Biotechnology

Popis: PRIME-XV MSC EXPANSION XSFM 1 * 250 mL

Měrná jednotka: 1 * 250 mL

New Product Akce

Katalogové číslo: (SHBT91201)

Dodavatel: Shenandoah Biotechnology

Popis: PRIME-XV NEURAL BASAL MEDIUM 1 * 500 mL

Měrná jednotka: 1 * 500 mL

New Product Akce