Hledali jste: ProSci Inc.

Katalogové číslo: (PRSI96-100)

Dodavatel: ProSci Inc.

Popis: CD83 antigen is also known as B-cell activation protein and Cell surface protein HB15. CD83 is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI91-283)

Dodavatel: ProSci Inc.

Popis: Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI36-156)

Dodavatel: ProSci Inc.

Popis: Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo.

Měrná jednotka: 1 * 500 µG

Akce

Katalogové číslo: (PRSI92-047)

Dodavatel: ProSci Inc.

Popis: Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI26-768)

Dodavatel: ProSci Inc.

Popis: The exact function of C15orf26 remains unknown.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI96-189)

Dodavatel: ProSci Inc.

Popis: C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI49-998)

Dodavatel: ProSci Inc.

Popis: Anti-ADORA2 Mouse Monoclonal Antibody

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI36-043)

Dodavatel: ProSci Inc.

Popis: Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI91-859)

Dodavatel: ProSci Inc.

Popis: Interleukin-21 receptor is also known as IL-21 receptor, IL-21R, CD360. In humans, it is encoded by the IL21R gene. It belongs to the type I cytokine receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSIXG-6139)

Dodavatel: ProSci Inc.

Popis: Anti-CYCS Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (PRSI98-963)

Dodavatel: ProSci Inc.

Popis: Anti-CD49b Rat Monoclonal Antibody [clone:DX5]

Měrná jednotka: 1 * 0,5 mg

Akce

Katalogové číslo: (PRSI13-242)

Dodavatel: ProSci Inc.

Popis: Anti-GATA2 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (PRSI13-198)

Dodavatel: ProSci Inc.

Popis: Anti-RALA Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (PRSI13-203)

Dodavatel: ProSci Inc.

Popis: Anti-HSPA9 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (PRSI13-253)

Dodavatel: ProSci Inc.

Popis: Anti-MMP7 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (PRSI64-048)

Dodavatel: ProSci Inc.

Popis: For WB starting dilution is: 1:1000.

Měrná jednotka: 1 * 400 µl

New Product Akce