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Katalogové číslo: (PRSI1151P)

Dodavatel: ProSci Inc.

Popis: ASK1 peptide is used for blocking the activity of ASK1 antibody.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI5645P)

Dodavatel: ProSci Inc.

Popis: TMEM70 peptide is used for blocking the activity of TMEM70 antibody.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI7337P)

Dodavatel: ProSci Inc.

Popis: 17 amino acids near the center of human ULK2.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI6067P)

Dodavatel: ProSci Inc.

Popis: ZNF687 peptide is used for blocking the activity of ZNF687 antibody.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (SIAL85102201-1VL)

Dodavatel: Merck

Popis: Established from the pleural effusion of a ductal carcinoma of the breast of a 54-year-old female. The cells carry receptors for a variety of steroids.

Měrná jednotka: 1 * 1 Vial

New Product Akce

Dodavatel: Shenandoah Biotechnology

Popis: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family and promotes endothelial cell growth and angiogenesis. PlGF is secreted as a homodimer and may also form a heterodimer with VEGF. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. Circulating PlGF levels are correlated with colorectal and renal cancers, as well as atherosclerosis and ischemic heart disease. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 lacks a heparin-binding domain and signals through the VEGFR-1 receptor.

New Product

Dodavatel: Shenandoah Biotechnology

Popis: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family and promotes endothelial cell growth and angiogenesis. PlGF is secreted as a homodimer and may also form a heterodimer with VEGF. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. Circulating PlGF levels are correlated with colorectal and renal cancers, as well as atherosclerosis and ischemic heart disease. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 lacks a heparin-binding domain and signals through the VEGFR-1 receptor.

New Product

Katalogové číslo: (PRSI92-051)

Dodavatel: ProSci Inc.

Popis: DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

Měrná jednotka: 1 * 0,05 mg

New Product Akce

Katalogové číslo: (PRSI91-089)

Dodavatel: ProSci Inc.

Popis: BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.

Měrná jednotka: 1 * 0,05 mg

New Product Akce

Katalogové číslo: (TB55)

Dodavatel: G-Biosciences

Popis: Ready to screen human cancer cell line blots.

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (PRSI10-229)

Dodavatel: ProSci Inc.

Popis: Anti-HuMax-CD20 Recombinant Antibody

Měrná jednotka: 1 * 0,1 mg

New Product Akce

Katalogové číslo: (ABCAAB133660-1ML)

Dodavatel: Abcam

Popis: Anti-Human IgA Rabbit Monoclonal Antibody [clone: EPSISR10]

Měrná jednotka: 1 * 1 mL

New Product Akce

Dodavatel: Apollo Scientific

Popis: (S)-(-)-2-(Boc-aminomethyl)-4,4-diethoxypiperidine fumarate

Katalogové číslo: (AVIVARP47515_P050)

Dodavatel: Aviva Systems Biology

Popis: Anti-DUXA Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (ABGEAP20379B)

Dodavatel: Abgent

Popis: Anti-CUTA Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 400 µl

Akce

Katalogové číslo: (IMMRIR2373)

Dodavatel: ImmunoReagents

Popis: Anti-IgG Human Polyclonal Antibody

Měrná jednotka: 1 * 10 mg

Akce