Hledali jste: odc1

Katalogové číslo: (BOSSBS-15371R-CY3)

Dodavatel: Bioss

Popis: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIO7050-02B)

Dodavatel: US Biological

Popis: Anti-ORC1 Rat Monoclonal Antibody [clone: 7H45]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ABCAAB72100-100)

Dodavatel: Abcam

Popis: Rabbit polyclonal to GPCR RDC1/CXCR-7.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (ANTIA308402-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to NDC1 for WB with samples derived from human, mouse and rat.

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (PRSI15-710)

Dodavatel: ProSci Inc.

Popis: Anti-ORC1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

Akce

Katalogové číslo: (ANTIA10402-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to MDC1 for WB, IHC and ICC/IF with samples derived from human.

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (PRSI79-916)

Dodavatel: ProSci Inc.

Popis: The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BIRBORB27343-5)

Dodavatel: Biorbyt

Popis: Anti-SDC1 Mouse Monoclonal Antibody

Měrná jednotka: 1 * 5 mL

Akce

 This is a MarketSource item. Additional charges may apply

Katalogové číslo: (ABNOPAB20340)

Dodavatel: Abnova

Popis: Rabbit polyclonal antibody raised against recombinant SDC1.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BSBTA01252-2)

Dodavatel: Boster Bio

Popis: Rabbit IgG polyclonal antibody for MDC1 detection. Tested with IHC-P, Direct ELISA in Human.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (USBI030838)

Dodavatel: US Biological

Popis: Anti-SDC1 Mouse Monoclonal Antibody [clone: 480CT5.4.3]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-15371R-CY5)

Dodavatel: Bioss

Popis: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-15371R-FITC)

Dodavatel: Bioss

Popis: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ABCAAB117836-100)

Dodavatel: Abcam

Popis: Rabbit polyclonal to GPCR RDC1/CXCR-7.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ABGEAM2142A)

Dodavatel: Abgent

Popis: Anti-SDC1 Mouse Monoclonal Antibody [clone: 587CT7.3.6.5]

Měrná jednotka: 1 * 0,1 mL

Akce

Katalogové číslo: (USBIC2548-63D)

Dodavatel: US Biological

Popis: Anti-SDC1 Mouse Monoclonal Antibody [clone: B-A38]

Měrná jednotka: 1 * 1 mL

Akce