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Anti-ALAS2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Katalogové číslo: (USBI031764-AP)

Dodavatel: US Biological

Popis: Anti-ALAS2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Měrná jednotka: 1 * 200 µl

Akce

N/A Each

Anti-ASB2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-2835R-A555)

Dodavatel: Bioss

Popis: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-MBD5 Mouse Monoclonal Antibody [clone: 4A12-1B6]

Katalogové číslo: (USBI129468)

Dodavatel: US Biological

Popis: Anti-MBD5 Mouse Monoclonal Antibody [clone: 4A12-1B6]

Měrná jednotka: 1 * 100 µG

Akce

N/A Each

Anti-INSR Mouse Monoclonal Antibody [clone: MM0414-2A12]

Katalogové číslo: (ABCAAB90940-100)

Dodavatel: Abcam

Popis: Anti-INSR Mouse Monoclonal Antibody [clone: MM0414-2A12]

Měrná jednotka: 1 * 100 µG

Akce

N/A Each

Anti-ALAS2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-9516R-HRP)

Dodavatel: Bioss

Popis: 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-AARS2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-1603R-FITC)

Dodavatel: Bioss

Popis: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.

Měrná jednotka: 1 * 100 µl

Akce