Hledali jste: Arabinofuranosyl-guanine+hydrate

Katalogové číslo: (BOSSBS-10035R-FITC)

Dodavatel: Bioss

Popis: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI151133)

Dodavatel: US Biological

Popis: Anti-VAV3 Goat Polyclonal Antibody

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BOSSBS-11235R)

Dodavatel: Bioss

Popis: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13245R-CY7)

Dodavatel: Bioss

Popis: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. G gamma4 interacts with beta-1 and beta-2, but not with beta-3. It is expressed in brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1161R-CY5)

Dodavatel: Bioss

Popis: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1161R)

Dodavatel: Bioss

Popis: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6962R-CY5)

Dodavatel: Bioss

Popis: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: MP Biomedicals

Popis: Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA. Guanine is a purine derivative.

Katalogové číslo: (BOSSBS-7768R-CY7)

Dodavatel: Bioss

Popis: Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1894R-CY3)

Dodavatel: Bioss

Popis: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI151396)

Dodavatel: US Biological

Popis: Anti-GNAT3 Goat Polyclonal Antibody

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (USBI036122-BIOTIN)

Dodavatel: US Biological

Popis: Anti-GNA11 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (BOSSBS-6962R-A750)

Dodavatel: Bioss

Popis: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6962R-A680)

Dodavatel: Bioss

Popis: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11582R-CY5)

Dodavatel: Bioss

Popis: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12866R-CY3)

Dodavatel: Bioss

Popis: Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects Golgi structure and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the Golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

Měrná jednotka: 1 * 100 µl

Akce