Hledali jste: masp

Katalogové číslo: (BOSSBS-1723R-A750)

Dodavatel: Bioss

Popis: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1723R-A680)

Dodavatel: Bioss

Popis: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (PRSI56-507)

Dodavatel: ProSci Inc.

Popis: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.

Měrná jednotka: 1 * 400 µl

New Product Akce

Katalogové číslo: (PRSI91-557)

Dodavatel: ProSci Inc.

Popis: Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (PRSI19-799)

Dodavatel: ProSci Inc.

Popis: Anti-MASP1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (PRSI16-385)

Dodavatel: ProSci Inc.

Popis: Anti-MASP2 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µl

New Product Akce

Katalogové číslo: (ANTIA76927-96)

Dodavatel: ANTIBODIES.COM

Popis: Human MASP1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human MASP1 in serum, plasma, tissue homogenates, and other biological fluids.

Měrná jednotka: 1 * 96 Tests

New Product Akce

Katalogové číslo: (ANTIA310414-96)

Dodavatel: ANTIBODIES.COM

Popis: Human MASP1 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i><i>in vitro</i></i> quantitative determination of human MASP1 in serum, plasma, and other biological fluids.

Měrná jednotka: 1 * 96 Tests

New Product Akce

Katalogové číslo: (ANTIA100991-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to MASP2 for WB and ELISA with samples derived from human.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (ANTIA100990-100)

Dodavatel: ANTIBODIES.COM

Popis: Rabbit polyclonal antibody to MASP2 for WB and ELISA with samples derived from human.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (ANTIA318830-100)

Dodavatel: ANTIBODIES.COM

Popis: Recombinant human monoclonal [Narsoplimab Biosimilar] antibody to MASP2 for flow cytometry with samples derived from human.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (ANTIA76928-96)

Dodavatel: ANTIBODIES.COM

Popis: Human MASP2 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human MASP2 in serum, plasma, tissue homogenates, and other biological fluids.

Měrná jednotka: 1 * 96 Tests

New Product Akce

Katalogové číslo: (ANTIA311250-96)

Dodavatel: ANTIBODIES.COM

Popis: Human MASP2 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i><i>in vitro</i></i> quantitative determination of human MASP2 in serum, plasma, and other biological fluids.

Měrná jednotka: 1 * 96 Tests

New Product Akce

Katalogové číslo: (ANTIA87259-96)

Dodavatel: ANTIBODIES.COM

Popis: Mouse MASP2 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse MASP2 in serum, plasma, tissue homogenates, and other biological fluids.

Měrná jednotka: 1 * 96 Tests

New Product Akce