Hledali jste: jak3

Katalogové číslo: (USBIJ0902-06J)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Monoclonal Antibody [clone: 10g85]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIJ0902-06)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 250 µG

Akce

Katalogové číslo: (USBI037180-HRP)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (AVIVARP54306_P050)

Dodavatel: Aviva Systems Biology

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (USBI037180)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (BOSSBS-2808R-A350)

Dodavatel: Bioss

Popis: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2808R)

Dodavatel: Bioss

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3208R)

Dodavatel: Bioss

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI030355)

Dodavatel: US Biological

Popis: Anti-JAK3 Mouse Monoclonal Antibody [clone: 13B433]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (AVIVARP54305_P050)

Dodavatel: Aviva Systems Biology

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (USBI037180-APC)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (ABGEAP14261A)

Dodavatel: Abgent

Popis: Anti-JAK3 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 400 µl

Akce

Katalogové číslo: (BWRLBS1671)

Dodavatel: Bioworld Technology

Popis: Synthetic peptide, corresponding to amino acids 750-800 of Human JAK3.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (USBIJ0902-04A)

Dodavatel: US Biological

Popis: Anti-JAK3 Mouse Monoclonal Antibody [clone: 9H144]

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (USBI037180-BIOTIN)

Dodavatel: US Biological

Popis: Anti-JAK3 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (BOSSBS-2808R-CY3)

Dodavatel: Bioss

Popis: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.

Měrná jednotka: 1 * 100 µl

Akce