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Katalogové číslo: (BOSSBS-5379R-HRP)
Dodavatel: Bioss
Popis: Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-3933R-A488)
Dodavatel: Bioss
Popis: Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-15420R-A647)
Dodavatel: Bioss
Popis: HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-0202R-FITC)
Dodavatel: Bioss
Popis: Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-7021R-A680)
Dodavatel: Bioss
Popis: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-15420R-A750)
Dodavatel: Bioss
Popis: HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
Měrná jednotka: 1 * 100 µl


Dodavatel: Biotium
Popis: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Katalogové číslo: (BOSSBS-6405R)
Dodavatel: Bioss
Popis: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-6894R-CY3)
Dodavatel: Bioss
Popis: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008].
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-12392R-CY7)
Dodavatel: Bioss
Popis: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-12392R-CY3)
Dodavatel: Bioss
Popis: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-1160R-CY5)
Dodavatel: Bioss
Popis: Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-6405R-CY7)
Dodavatel: Bioss
Popis: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-6405R-CY3)
Dodavatel: Bioss
Popis: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Měrná jednotka: 1 * 100 µl


Katalogové číslo: (BOSSBS-6405R-CY5)
Dodavatel: Bioss
Popis: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Měrná jednotka: 1 * 100 µl


Dodavatel: Biotium
Popis: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

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