Hledali jste: COWIE

Popis: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyses the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.

Katalogové číslo: BOSSBS-0092R-A750

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

Katalogové číslo: BOSSBS-5487R-A488

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Katalogové číslo: BOSSBS-8468R

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Katalogové číslo: BOSSBS-9358R-A488

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Katalogové číslo: BOSSBS-9358R-A555

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Katalogové číslo: BOSSBS-9358R

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyses the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.

Katalogové číslo: BOSSBS-0092R-A680

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.

Katalogové číslo: BOSSBS-9351R-CY3

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Katalogové číslo: BOSSBS-8468R-CY5.5

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Katalogové číslo: BOSSBS-8468R-CY7

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Katalogové číslo: BOSSBS-9358R-HRP

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Also known as Appetite regulating hormone; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524. Sequence notes: Gly-Ser-Ser-Phe-Leu-Ser-Pro- Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu- Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg (mo, rat).

Katalogové číslo: BOSSBS-1375R-A555

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Kyselina L(+)-glutamová 98.5-101.5% USP, Multi-Compendial, J.T.Baker®

Katalogové číslo: 2077-06

Měrná jednotka: 1 * 1 kg

Dodavatel: Avantor

Bezpečnostní list Certifikáty Akce

Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Katalogové číslo: BOSSBS-8468R-A680

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Katalogové číslo: BOSSBS-8468R-A750

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The proteasome is a multicatalytic proteinase complex which is characterised by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Katalogové číslo: BOSSBS-9358R-A750

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce