Hledali jste: chimaerin

Katalogové číslo: (BOSSBS-11539R)

Dodavatel: Bioss

Popis: The Rac-GAP chimaerin family member Alpha-chimaerin (also known as N-chimaerin or rho GTPase-activating protein 2) has two splice variants: Alpha1 and Alpha2. The ?-chimaerin variant is a neuron-specific, diacylglycerol-binding and GTPase-activating protein for ras-related protein Rac 1. This variant lacks the N-terminal SH2 domain that is present in the Alpha2 variant. By inactivating Rac 1, Alpha1-chimaerin plays a significant role in the regulation of dendritic growth during neuronal development. It is recruited to the plasma membrane by phospholipase C Beta-coupled cell surface receptors activating the downstream generation of DAG (diacylglycerol). Overexpression of Alpha1-chimaerin results in dendritic spine retraction and the loss of dendritic branches. In the presence of reduced neuronal activity, Alpha1-chimaerin expression is down-regulated resulting in an increase in spine growth and dendritic branching.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI033856)

Dodavatel: US Biological

Popis: Anti-CHN1 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI033858-BIOTIN)

Dodavatel: US Biological

Popis: Anti-CHN2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI033858)

Dodavatel: US Biological

Popis: Anti-CHN2 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (ANTIA82874-100)

Dodavatel: ANTIBODIES.COM

Popis: Goat polyclonal antibody to CHN2 for ELISA and IHC with samples derived from human.

Měrná jednotka: 1 * 100 µG

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