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Image Unavailable-BOSSBS-12215R-A488

Anti-ZNF266 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-12215R-A488)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12215R-A555

Anti-ZNF266 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-12215R-A555)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5161R-A680

Anti-CAPZA1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-5161R-A680)
Dodavatel: Bioss
Popis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ROCKMB-103-1000

DNA (Deoxyribonucleic acid) (from salmon testes)

Katalogové číslo: (ROCKMB-103-1000)
Dodavatel: Rockland Immunochemicals
Popis: DNA from salmon is commonly used in the preparation of pre-hybridisation and hybridisation solutions. These prepared solutions are used to block the non-specific attachment of probe to the surface of a membrane. The DNA solutions are prepared from highly pure, phenol/chloroform-extracted DNA, and DNase- and RNase-free (DEPC-treated) distilled, deionised water.
Měrná jednotka: 1 * 1 g
Image Unavailable-BOSSBS-6480R-CY5

Anti-CH25H Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-6480R-CY5)
Dodavatel: Bioss
Popis: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-8027R-A750

Anti-CNIH2/3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-8027R-A750)
Dodavatel: Bioss
Popis: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitisation. CNIH2 also blocks CACNG8-mediated resensitisation of AMPA receptors.
Měrná jednotka: 1 * 100 µl
Image Unavailable-733-1967

Accessories and consumables for KingFisher™ Flex

Dodavatel: Thermo Fisher Scientific
Popis: Automated nucleic acid purification system, accessory, KingFisher™ Flex zahřívací blok na 96 vzorků (hluboké dno)

Image Unavailable-BOSSBS-6675R-A680

Anti-KCNN4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-6675R-A680)
Dodavatel: Bioss
Popis: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarisation which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2374R-CY7

Anti-C9ORF172 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-2374R-CY7)
Dodavatel: Bioss
Popis: TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2374R-CY3

Anti-C9ORF172 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-2374R-CY3)
Dodavatel: Bioss
Popis: TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13334R-A555

Anti-GEN1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-13334R-A555)
Dodavatel: Bioss
Popis: Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6480R-A680

Anti-CH25H Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-6480R-A680)
Dodavatel: Bioss
Popis: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesising a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0492R-A555

Anti-RGS2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-0492R-A555)
Dodavatel: Bioss
Popis: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0492R-A647

Anti-RGS2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-0492R-A647)
Dodavatel: Bioss
Popis: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6675R-A350

Anti-KCNN4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-6675R-A350)
Dodavatel: Bioss
Popis: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11859R-A488

Anti-ITM2C Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-11859R-A488)
Dodavatel: Bioss
Popis: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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