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Image Unavailable-ROCKMB-103-1000

DNA (Deoxyribonucleic acid) (from salmon testes)

Katalogové číslo: (ROCKMB-103-1000)
Dodavatel: Rockland Immunochemicals
Popis: DNA from salmon is commonly used in the preparation of pre-hybridisation and hybridisation solutions. These prepared solutions are used to block the non-specific attachment of probe to the surface of a membrane. The DNA solutions are prepared from highly pure, phenol/chloroform-extracted DNA, and DNase- and RNase-free (DEPC-treated) distilled, deionised water.
Měrná jednotka: 1 * 1 g
Image Unavailable-BOSSBS-5161R-A680

Anti-CAPZA1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-5161R-A680)
Dodavatel: Bioss
Popis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9051R-CY3

Anti-TRPM4 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-9051R-CY3)
Dodavatel: Bioss
Popis: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9051R-CY5.5

Anti-TRPM4 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-9051R-CY5.5)
Dodavatel: Bioss
Popis: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOALX380100C100

Leptomycin B 0,2 mg/ml ≥98% (by HPLC)

Katalogové číslo: (ENZOALX380100C100)
Dodavatel: ENZO LIFE SCIENCES
Popis: A potent and specific nuclear export inhibitor. In addition to antifungal and antibacterial activities, blocks the cell cycle and is a potent anti-tumor agent.
Měrná jednotka: 1 * 100 µG
Image Unavailable-BOSSBS-8027R-A750

Anti-CNIH2/3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-8027R-A750)
Dodavatel: Bioss
Popis: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitisation. CNIH2 also blocks CACNG8-mediated resensitisation of AMPA receptors.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BC91

Sulphosuccinimidyl acetate (Sulpho-NHS-acetate)

Katalogové číslo: (BC91)
Dodavatel: G-Biosciences
Popis: Sulpho NHS acetate is a small, water-soluble compound used for blocking primary amines by acylation. It covalent bonds with amine groups to prevent specific interactions and conjugations. It is water-soluble and reacts at pH 7 to 9.
Měrná jednotka: 1 * 100 mg

Certifikáty


Image Unavailable-BOSSBS-7527R

Anti-FAIM3 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-7527R)
Dodavatel: Bioss
Popis: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.Tissue specificity: Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6675R-A350

Anti-KCNN4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-6675R-A350)
Dodavatel: Bioss
Popis: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Měrná jednotka: 1 * 100 µl
Product Image-631-1082

Microtome blades

Dodavatel: LEICA HISTOLOGY
Popis: With these blades it is easy to section a wide range of tissues. Edge encourages immediate ribboning. Premium edge geometry with 35° angle, so no adjustments are needed for the microtome. The uniform coating plus fine and consistent honing helps eliminating sectioning variation. A durable cutting edge is warranted. Quality of each section block-after-block. Expected results with each blade in the dispenser and between different lots will be achieved. There are no sharp corners. When the blade is positioned in the blade holder assembly of the microtome, the blade is fully covered except for the cutting edge.

Image Unavailable-ENZOBMLGR2120050

2-Chloro-5-nitro-N-(4-pyridyl)benzamide ≥98% (by TLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Potent and selective PPARγ antagonist. T0070907 blocks PPARγ function in both cell-based reporter gene and adipocyte differentiation assays. It inhibits growth and survival of hepatocellular carcinoma cells and squamous cell carcinoma cell lines by interfering with cell adhesion "anoikis".

Image Unavailable-89381.A1

Křemelina -325 Mesh Powder

Dodavatel: Thermo Fisher Scientific
Popis: Kieselguhr is used in used as a filtration aid, mild abrasive in products including metal polishes and toothpaste, absorbent for liquids, matting agent for coatings, reinforcing filler in plastics and rubber, anti-block in plastic films, porous support for chemical catalysts, cat litter, activator in blood clotting studies, a stabilizing component of dynamite, and a thermal insulator.

Bezpečnostní list Certifikáty

Product Image-S040J-500

Calf serum

Dodavatel: Biowest
Popis: Calf serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Calf serum is used as a blocking agent in immunoassays and controls.

Image Unavailable-BOSSBS-2374R-A750

Anti-TAP2/ABCB3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-2374R-A750)
Dodavatel: Bioss
Popis: TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
Měrná jednotka: 1 * 100 µl
Product Image-S2160-500

Mouse serum

Dodavatel: Biowest
Popis: Mouse serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Mouse serum is used as a blocking agent in immunoassays and controls.

Image Unavailable-BOSSBS-1346R-HRP

Anti-TRP73 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-1346R-HRP)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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