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Image Unavailable-BOSSBS-1346R-A680

Anti-Tp73 Protein Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-1346R-A680)
Dodavatel: Bioss
Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Měrná jednotka: 1 * 100 µl
Product Image-LBCP7482200

Dry evaporation systems, N₂/48, RapidVap®

Dodavatel: LABCONCO
Popis: This system uses nitrogen blow down, vortex motion and heat to speed evaporation of up to 48 small samples or eight 450 milliliter samples at once.

Image Unavailable-BOSSBS-9051R-A488

Anti-TRPM4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-9051R-A488)
Dodavatel: Bioss
Popis: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) >K(+) >Cs(+) >Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]. It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together. It leads to complete atrio-ventricular block causing syncope and sudden death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOALX350336MC05

Galiellalactone (from unidentified fungus MST-FP1888) ≥95% (by HPLC)

Katalogové číslo: (ENZOALX350336MC05)
Dodavatel: ENZO LIFE SCIENCES
Popis: Originally isolated from Galiella rufa as a plant growth regulator. Inhibits IL-6 mediated signal transduction by blocking the binding of the activated STAT3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation site of the STAT3 transcription factor.
Měrná jednotka: 1 * 0,5 mg
Image Unavailable-BOSSBS-12215R-CY5

Anti-ZNF266 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-12215R-CY5)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12215R

Anti-ZNF266 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-12215R)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
Měrná jednotka: 1 * 100 µl
Product Image-SCTV106478

Safety waste caps and ventilation kit, SymLine®

Dodavatel: S.C.A.T.
Popis: Safety waste caps safely connect pipework to the waste container. The integrated exhaust filter blocks solvent vapours, for the protection of health and the environment.

Image Unavailable-BOSSBS-8027R-A680

Anti-CNIH2/3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-8027R-A680)
Dodavatel: Bioss
Popis: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitisation. CNIH2 also blocks CACNG8-mediated resensitisation of AMPA receptors.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6625R-CY5.5

Anti-INSIG2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-6625R-CY5.5)
Dodavatel: Bioss
Popis: Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2509R-A488

Anti-AIMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-2509R-A488)
Dodavatel: Bioss
Popis: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2509R-A350

Anti-AIMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-2509R-A350)
Dodavatel: Bioss
Popis: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5161R-CY7

Anti-CAPZA1 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-5161R-CY7)
Dodavatel: Bioss
Popis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6675R-CY5

Anti-KCNN4 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-6675R-CY5)
Dodavatel: Bioss
Popis: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6675R-CY3

Anti-KCNN4 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-6675R-CY3)
Dodavatel: Bioss
Popis: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Měrná jednotka: 1 * 100 µl
Product Image-S2150-050

Rat serum

Dodavatel: Biowest
Popis: Rat serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Rat serum is used as a blocking agent in immunoassays and controls.

Image Unavailable-BOSSBS-12215R-A488

Anti-ZNF266 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-12215R-A488)
Dodavatel: Bioss
Popis: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
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Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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