Hledali jste: ackr2

Katalogové číslo: (USBIA0855-95C)

Dodavatel: US Biological

Popis: Anti-ACVR1 Goat Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (USBI031594-BIOTIN)

Dodavatel: US Biological

Popis: Anti-ACVR2B Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI031593-BIOTIN)

Dodavatel: US Biological

Popis: Anti-ACVR2A Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI031547-BIOTIN)

Dodavatel: US Biological

Popis: Anti-ACOX2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA0760-26K)

Dodavatel: US Biological

Popis: Anti-ACTA2 Rabbit Polyclonal Antibody AMCA

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (BOSSBS-12415R-CY7)

Dodavatel: Bioss

Popis: Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1–6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12416R-CY5)

Dodavatel: Bioss

Popis: Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12414R-CY5)

Dodavatel: Bioss

Popis: MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0801R-CY3)

Dodavatel: Bioss

Popis: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B through FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor (By similarity).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5030R-CY5)

Dodavatel: Bioss

Popis: ACOX2

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7952R-CY5)

Dodavatel: Bioss

Popis: ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-10367R-CY5)

Dodavatel: Bioss

Popis: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI031534-BIOTIN)

Dodavatel: US Biological

Popis: Anti-ACER1 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI031565-BIOTIN)

Dodavatel: US Biological

Popis: Anti-ACSS2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI034483-BIOTIN)

Dodavatel: US Biological

Popis: Anti-CCAR2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA0856-10B)

Dodavatel: US Biological

Popis: Anti-ACVR2B Goat Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 50 µG

Akce