Hledali jste: ack2

Katalogové číslo: (BOSSBS-5002R-A647)

Dodavatel: Bioss

Popis: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5002R-A350)

Dodavatel: Bioss

Popis: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4280R-A647)

Dodavatel: Bioss

Popis: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1227R-A750)

Dodavatel: Bioss

Popis: Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. May be involved both in adult synaptic function and plasticity and in brain development. Activates AKT1 by phosphorylating it on 'Tyr-176'. Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs). Phosphorylates WWOX on 'Tyr-287'. Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins. Contributes to the control of AXL receptor levels. Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7952R-A555)

Dodavatel: Bioss

Popis: ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI044445)

Dodavatel: US Biological

Popis: Anti-ACE2 Mouse Monoclonal Antibody (Biotin) [clone: AC384]

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (USBI031622-AP)

Dodavatel: US Biological

Popis: Anti-ADCK2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA0660-02A-HRP)

Dodavatel: US Biological

Popis: Anti-ACO2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA0560-22C)

Dodavatel: US Biological

Popis: Anti-ACP2 Mouse Monoclonal Antibody [clone: M1-4A12]

Měrná jednotka: 1 * 50 µG

Akce

Katalogové číslo: (ABCAAB321302-100UL)

Dodavatel: Abcam

Popis: Anti-PCK2 Rabbit Monoclonal Antibody [clone: EPR14224] (Alexa Fluor® 750)

Měrná jednotka: 1 * 100 µl

New Product Akce

Katalogové číslo: (BOSSBS-1004R-A488)

Dodavatel: Bioss

Popis: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ABCAAB308378-100)

Dodavatel: Abcam

Popis: Anti-ACE2 Rabbit Monoclonal Antibody [clone: HL1092]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBIA0882-66A-BIOT)

Dodavatel: US Biological

Popis: Anti-AK2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBIA0882-66B-BIOT)

Dodavatel: US Biological

Popis: Anti-AK2 Rabbit Polyclonal Antibody (Biotin)

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (ABCAAB211890-100)

Dodavatel: Abcam

Popis: Anti-AK2 Rabbit Monoclonal Antibody [clone: EPR11388(B)] (Alexa Fluor® 647)

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5002R-A750)

Dodavatel: Bioss

Popis: Catalyses the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

Měrná jednotka: 1 * 100 µl

Akce