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TriLink® 2'-Fluoro-2'-deoxycytidine-5'-Triphosphate

Dodavatel: TriLink BioTechnologies

Popis: 2'-Fluoro NTPs are being utilised in an increasing number of applications in research and new drug development. 2'-Fluoro-dCTP is incorporated in both DNA and RNA constructs to improve in vivo stability.

New Product

TriLink® 5-Propargylamino-2'-deoxyuridine-5'-Triphosphate

Dodavatel: TriLink BioTechnologies

Popis: 5-Propargylamino-2'-deoxyuridine can be enzymatically incorporated into DNA and cDNA to introduce primary amine groups. Primary amines can be labeled with NHS ester fluors and haptens for detection and immobilisation of the resulting DNA strand.

New Product

TriLink® CleanCap® M6 mCherry mRNA (N1MePsU)

Dodavatel: TriLink BioTechnologies

Popis: mCherry mRNA encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.

New Product

TriLink® CleanCap® Cas9 mRNA

Dodavatel: TriLink BioTechnologies

Popis: Cas9 mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform double stranded DNA cleavage.

New Product

TriLink® Sulf Cyanine5 Aminoallyluridine-5'-Triphosphate

Dodavatel: TriLink BioTechnologies

Popis: Cyanine 5-Aminoallyluridine-5'-Triphosphate is a substrate for T7 RNA polymerase, allowing the incorporation of cyanine 5 into RNA and mRNA during in vitro transcription. Cyanine 5 incorporation allows for fluorescent detection of RNA and mRNA independent of protein translation.

New Product

TriLink® CleanCap® M6 Cas9 mRNA (N1MePsU)

Dodavatel: TriLink BioTechnologies

Popis: Cas9 mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform double-stranded DNA cleavage.

New Product

TriLink® CleanCap® EGFP mRNA

Dodavatel: TriLink BioTechnologies

Popis: The EGFP mRNA expresses an enhanced version of the green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. EGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm.

TriLink® CleanCap® Cas9 mRNA (5 moU)

Dodavatel: TriLink BioTechnologies

Popis: Cas9 mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest, and the Cas9 protein is employed to perform double-stranded DNA cleavage.

TriLink® CleanCap® Cre mRNA (5 moU)

Dodavatel: TriLink BioTechnologies

Popis: NLS-Cre Recombinase mRNA is a capped and polyadenylated messenger RNA encoding Cre recombinase fused to a nuclear localisation sequence (NLS). Cre recombinase is a tyrosine recombinase that catalyzes recombination between two loxP sites.

New Product

TriLink® CleanCap® M6 EPO mRNA (N1MePsU)

Dodavatel: TriLink BioTechnologies

Popis: EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.

New Product

TriLink® CleanCap® FLuc mRNA (5 moU)

Dodavatel: TriLink BioTechnologies

Popis: The FLuc mRNA expresses a luciferase protein, originally isolated from the firefly, Photinus pyralis. FLuc is commonly used in mammalian cell culture to measure both gene expression and cell viability. It emits bioluminescence in the presence of the substrate, luciferin.

TriLink® CleanCap® EPO mRNA (5moU)

Dodavatel: TriLink BioTechnologies

Popis: EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.

New Product