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Popis: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.Tissue specificity:Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells.
Katalogové číslo: BOSSBS-7920R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Katalogové číslo: BOSSBS-5487R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.
Katalogové číslo: BOSSBS-7103R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.
Katalogové číslo: BOSSBS-6869R-CY7
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Katalogové číslo: BOSSBS-5809R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0058R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Katalogové číslo: BOSSBS-1346R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. ProRS (Prolyl-tRNA synthetase), also known as EPRS, EARS, PARS, QARS, QPRS, PIG32 or GLUPRORS, is a 1,512 amino acid protein that contains three WHEP-TRS domains and belongs to both the class-I and class-II aminoacyl-tRNA synthetase family. Functioning as a component of the multisynthase complex, ProRS uses ATP to catalyze the conversion of L-glutamate and tRNA(Glu) to L-glutamyl-tRNA(Glu), as well as the conversion of L-proline and tRNA(Pro) to L-prolyl-tRNA(Pro).
Katalogové číslo: BOSSBS-13393R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterised by the presence of atleast one Bcl-2 homology (BH) domains.
Katalogové číslo: ENZOADIAAM140E
Měrná jednotka: 1 * 100 µG
Dodavatel: ENZO LIFE SCIENCES


Popis: Control large loads—SPDT relay(s) rated 250 VAC, 10 A resistive.
Katalogové číslo: MFLX43300-32
Měrná jednotka: 1 * 1 KS
Dodavatel: Avantor Fluid Handling

CSA Certified


Popis: Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).
Katalogové číslo: BOSSBS-5760R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Rabbit polyclonal to NRG1.
Katalogové číslo: ABCAAB217805-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Easily mounts to any sensor or fitting assembly.
Katalogové číslo: MFLX43300-22
Měrná jednotka: 1 * 1 KS
Dodavatel: Avantor Fluid Handling


Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Katalogové číslo: BOSSBS-1346R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Katalogové číslo: BOSSBS-1346R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Katalogové číslo: BOSSBS-1346R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss