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Image Unavailable-BOSSBS-11043R-A647

Anti-BEST4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-11043R-A647)
Dodavatel: Bioss
Popis: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11043R-FITC

Anti-BEST4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-11043R-FITC)
Dodavatel: Bioss
Popis: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11043R-A488

Anti-BEST4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-11043R-A488)
Dodavatel: Bioss
Popis: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3807R-CY5

Anti-PLAA Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-3807R-CY5)
Dodavatel: Bioss
Popis: Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0013R-A750

Anti-CYC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-0013R-A750)
Dodavatel: Bioss
Popis: Electron carrier protein. The oxidised form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0013R-CY3

Anti-CYCS Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-0013R-CY3)
Dodavatel: Bioss
Popis: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9687R-CY7

Anti-BLNK Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-9687R-CY7)
Dodavatel: Bioss
Popis: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9687R-CY5.5

Anti-BLNK Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-9687R-CY5.5)
Dodavatel: Bioss
Popis: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9688R-CY5

Anti-BLNK Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-9688R-CY5)
Dodavatel: Bioss
Popis: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7674R-CY3

Anti-TMEM123 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-7674R-CY3)
Dodavatel: Bioss
Popis: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9097R-A488

Anti-ANKS1B Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-9097R-A488)
Dodavatel: Bioss
Popis: The β-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer’s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.
Měrná jednotka: 1 * 100 µl
Product Image-PRSI36-186

Anti-BIMS/EL/L Rat Monoclonal Antibody [clone: 10B12]

Katalogové číslo: (PRSI36-186)
Dodavatel: ProSci Inc.
Popis: Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
Měrná jednotka: 1 * 100 µG
Image Unavailable-BOSSBS-5424R-CY5

Anti-TAB3 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-5424R-CY5)
Dodavatel: Bioss
Popis: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5424R-CY7

Anti-TAB3 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-5424R-CY7)
Dodavatel: Bioss
Popis: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11408R-A680

Anti-ACTHR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-11408R-A680)
Dodavatel: Bioss
Popis: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
Měrná jednotka: 1 * 100 µl
Product Image-SOLUL-7206-5

TriLink® CleanCap® Cas9 mRNA (5 moU)

Dodavatel: TriLink BioTechnologies
Popis: Cas9 mRNA expresses a version of the <em>Streptococcus pyogenes</em> SF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest, and the Cas9 protein is employed to perform double-stranded DNA cleavage.

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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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