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Product Image-GRANB-2N

Blocks for TS-DW Thermoshaker

Dodavatel: GRANT INSTRUMENTS
Popis: Blocks for TS-DW Thermoshaker

New Product

Product Image-ABNOMAB0009

Anti-LATS2 Mouse Monoclonal Antibody [clone: ST-3B11]

Katalogové číslo: (ABNOMAB0009)
Dodavatel: Abnova
Popis: Mouse monoclonal antibody raised against synthetic phosphopeptide of LATS2.
Měrná jednotka: 1 * 100 µG

Nové řešení transparentnosti pro evropské zákazníky

Všimli jste si naší nově zlepšené viditelnosti rozmístění zásob u pokladny?

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Zlepšení rozmístění zásob

Image Unavailable-BOSSBS-10994R-CY7

Anti-PRKDC Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-10994R-CY7)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10994R

Anti-PRKDC Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-10994R)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
Měrná jednotka: 1 * 100 µl
Product Image-17-5068-01

Reversed phase FPLC columns, SOURCE™ 15RPC ST

Katalogové číslo: (17-5068-01)
Dodavatel: Cytiva
Popis: Source 15RPC ST 4.6/100 is a prepacked stainless steel column which provides fast, high-capacity preparative protein purification with reversed phase chromatography.
Měrná jednotka: 1 * 1 KS
Product Image-ABNOH00000412-A01

Anti-STS Mouse Polyclonal Antibody

Katalogové číslo: (ABNOH00000412-A01)
Dodavatel: Abnova
Popis: Anti-STS Mouse Polyclonal Antibody
Měrná jednotka: 1 * 50 µl
Product Image-PRSI25-714

Anti-STS Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI25-714)
Dodavatel: ProSci Inc.
Popis: STS catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in its gene are known to cause X-linked ichthyosis The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Měrná jednotka: 1 * 50 µG
Product Image-ABNOPAB7370

Anti-STS Goat Polyclonal Antibody

Katalogové číslo: (ABNOPAB7370)
Dodavatel: Abnova
Popis: Goat polyclonal antibody raised against synthetic peptide of STS.
Měrná jednotka: 1 * 100 µl
Product Image-BIRBORB19638-100

Anti-STS Goat Polyclonal Antibody

Katalogové číslo: (BIRBORB19638-100)
Dodavatel: Biorbyt
Popis: Anti-STS Goat Polyclonal Antibody
Měrná jednotka: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-WITG3.580.303

Spare parts for automatic pipettes

Dodavatel: WITEG LABORTECHNIK
Popis: Bottle top tilt measure, Dispensing head only, 4 ml, for automatic pipettes with reservoir bottle, ST 29/32, Objem: 4 ml

Product Image-WITG2.147.000

Sprayer for chromatography

Katalogové číslo: (WITG2.147.000)
Dodavatel: WITEG LABORTECHNIK
Popis: Sprayer are made of borosilicate glass, complete with rubber bulb.
Měrná jednotka: 1 * 1 KS
Product Image-BHITLH-X791001

Optifit pipette tips, 10 - 1000 µl, extended, ST (10x96)

Dodavatel: Sartorius
Popis: The Optifit Extended Plus tips are designed to improve pipetting reach, making them ideal for use with deep and narrow labware. The tip design allows for more efficient retrieval of samples, down to the last drop. The longer length of these tips helps prevent contamination by ensuring that the pipette does not come into contact with the walls of labware or containers during use.

New Product

Image Unavailable-BOSSBS-1370R-A750

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-1370R-A750)
Dodavatel: Bioss
Popis: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
Měrná jednotka: 1 * 100 µl
Product Image-EBRO1340-5810

pH meters, handheld, PHT 810 / ST 1000

Dodavatel: EBRO
Popis: This portable instrument measures the pH value in meat, cold cuts, cheese, dairy products and fluids. It is therefore ideal for butchers, super markets and in the beverage production.

Image Unavailable-BOSSBS-5130R-FITC

Anti-PRKDC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-5130R-FITC)
Dodavatel: Bioss
Popis: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D. Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 'Ser-588' and increasing CRY1 protein stability, most likely through an indirect machanism. Interacts with CRY1 and CRY2; negatively regulates CRY1 phosphorylation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1370R-A488

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-1370R-A488)
Dodavatel: Bioss
Popis: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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