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Image Unavailable-BOSSBS-1021R-A555

Anti-TLR4 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-1021R-A555)
Dodavatel: Bioss
Popis: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-20595R-A680

Anti-TLR4 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Katalogové číslo: (BOSSBS-20595R-A680)
Dodavatel: Bioss
Popis: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-20594R-A750

Anti-TLR4 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Katalogové číslo: (BOSSBS-20594R-A750)
Dodavatel: Bioss
Popis: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Měrná jednotka: 1 * 100 µl
Image Unavailable-O7381-1AMP

Supelco® Organic Reference Standard, F.A.M.E. Mix RM-4

Katalogové číslo: (O7381-1AMP)
Dodavatel: Merck
Popis: Palmitic acid methyl ester (C16:0) 11,0% Stearic acid methyl ester (C18:0) 3,0% Oleic acid methyl ester (C18:1<i>cis</i>-9) 80,0% Linoleic acid methyl ester (C18:2<i>cis</i>-912) 6,0%.
Měrná jednotka: 1 * 1 Ampoul
Image Unavailable-BOSSBS-20595R-A750

Anti-TLR4 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Katalogové číslo: (BOSSBS-20595R-A750)
Dodavatel: Bioss
Popis: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Měrná jednotka: 1 * 100 µl
Image Unavailable-O7631-1AMP

Supelco® Organic Reference Standard, F.A.M.E. Mix RM-6

Katalogové číslo: (O7631-1AMP)
Dodavatel: Merck
Popis: Myristic acid methyl ester (C14:0) 2,0% Palmitic acid methyl ester (C16:0) 30,0% Palmitoleic acid methyl ester (C16:1<i>cis</i>-9) 3,0% Stearic acid methyl ester (C18:0) 14,0% Oleic acid methyl ester (C18:1<i>cis</i>-9) 41,0% Linoleic acid methyl ester (C18:2<i>cis</i>-912) 7,0% Linolenic acid methyl ester (C18:3<i>cis</i>-91215) 3,0%.
Měrná jednotka: 1 * 1 Ampoul
Image Unavailable-PRSI92-096

Human recombinant Lysophospholipase II (from E. coli)

Katalogové číslo: (PRSI92-096)
Dodavatel: ProSci Inc.
Popis: Acyl-Protein Thioesterase 2 is a cytoplasmic protein that belongs to the AB Hydrolase 2 family. LYPLA2 is a lysophospholipase and hydrolyses fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. LYPLA2 has hydrolase activity that converts Palmitoyl-protein to palmitate and protein. LYPLA2 regulates the multifunctional lysophospholipids by acting on biological membranes. LYPLA2 participates in Glycerophospholipid metabolism pathway, fatty acid metabolic process and lipid metabolic process.
Měrná jednotka: 1 * 50 µG
Image Unavailable-BOSSBS-20594R-A680

Anti-TLR4 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Katalogové číslo: (BOSSBS-20594R-A680)
Dodavatel: Bioss
Popis: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.
Měrná jednotka: 1 * 100 µl
Image Unavailable-O7006-1AMP

Supelco® Organic Reference Standard, F.A.M.E. Mix RM-1

Katalogové číslo: (O7006-1AMP)
Dodavatel: Merck
Popis: Palmitic acid methyl ester (C16:0) 6,0% Stearic acid methyl ester (C18:0) 3,0% Oleic acid methyl ester (C18:1<i>cis</i>-9) 35,0% Linoleic acid methyl ester (C18:2<i>cis</i>-912) 50,0% Linolenic acid methyl ester (C18:3<i>cis</i>-91215) 3,0% Arachidic acid methyl ester (C20:0) 3,0%.
Měrná jednotka: 1 * 1 Ampoul
Image Unavailable-PRSI91-259

Human recombinant Hydroxyacid Oxidase 1 (from E. coli)

Katalogové číslo: (PRSI91-259)
Dodavatel: ProSci Inc.
Popis: Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent alpha-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate, but it can also be active on 2-Hydroxy fatty acids, with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.
Měrná jednotka: 1 * 50 µG
Image Unavailable-O7256-1AMP

Supelco® Organic Reference Standard, F.A.M.E. Mix RM-3

Katalogové číslo: (O7256-1AMP)
Dodavatel: Merck
Popis: Myristic acid methyl ester (C14:0) 1,0% Palmitic acid methyl ester (C16:0) 4,0% Stearic acid methyl ester (C18:0) 3,0% Oleic acid methyl ester (C18:1<i>cis</i>-9) 45,0% Linoleic acid methyl ester (C18:2<i>cis</i>-912) 15,0% Linolenic acid methyl ester (C18:3<i>cis</i>-91215) 3,0% Arachidic acid methyl ester (C20:0) 3,0% Behenic acid methyl ester (C22:0) 3,0% Erucic acid methyl ester (C22:1<i>cis</i>-13) 20,0% Lignoceric acid methyl ester (C24:0) 3,0%.
Měrná jednotka: 1 * 1 Ampoul
Image Unavailable-PRSI91-506

Human recombinant Apolipoprotein M (from cells)

Katalogové číslo: (PRSI91-506)
Dodavatel: ProSci Inc.
Popis: Apolipoprotein M is a secreted protein which belongs to the Lipocalin family. ApoM often presents in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL). The ApoM gene encoded protein is expressed in liver and kidney, secreted through the plasma membrane but remains membrane-bound. ApoM probably involved in lipid transport. ApoM can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. The expression of ApoM could be regulated by platelet activating factor (PAF), Transforming Growth Factors (TGF), Insulin-Like Growth factor (IGF) and Leptin.
Měrná jednotka: 1 * 50 µG
Product Image-PRSI4571

Anti-ELOVL6 Rabbit Polyclonal Antibody

Katalogové číslo: (PRSI4571)
Dodavatel: ProSci Inc.
Popis: ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
Měrná jednotka: 1 * 100 µG
Product Image-X218-500G

MES sodium salt ≥98%, Reagent Grade

Katalogové číslo: (X218-500G)
Dodavatel: VWR Chemicals
Popis: MES sodium salt ≥98%, Reagent Grade
Měrná jednotka: 1 * 500 g

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Product Image-87715.180

Sodium picrate 13 g/l in aqueous solution Reag. Ph. Eur. 1065802

Katalogové číslo: (87715.180)
Dodavatel: VWR Chemicals
Popis: Sodium picrate 13 g/l in aqueous solution Reag. Ph. Eur. 1065802
Měrná jednotka: 1 * 100 mL

Bezpečnostní list Certifikáty


Product Image-26069.081

Sodium tetrachloroaurate dihydrate, TECHNICAL

Katalogové číslo: (26069.081)
Dodavatel: VWR Chemicals
Popis: Sodium tetrachloroaurate dihydrate, TECHNICAL
Měrná jednotka: 1 * 1 g

Bezpečnostní list Certifikáty


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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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