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Product Image-731-0750

Sealing tape, light blocking, non-fluorescent, Nunc™

Katalogové číslo: (731-0750)
Dodavatel: Thermo Fisher Scientific
Popis: Vinyl film with pressure sensitive acrylate adhesive. For application to plate top or bottom, to protect light sensitive samples.
Měrná jednotka: 1 * 50 KS

Environmentally Preferable


Product Image-BRDY150759

BradyJet™ J2000 Safety Marine Labels, White

Dodavatel: Brady
Popis: The British standard BS 5609 sets durability criteria for printed pressure-sensitive, adhesive-coated labels used when shipping chemical drums by sea.

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Image Unavailable-BOSSBS-6634R-A555

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-6634R-A555)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-CY5.5

Anti-XPC Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-6634R-CY5.5)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENTE202-122-01

Pneumatically operated diaphragm valves, Integra®

Dodavatel: ENTEGRIS
Popis: Available compliant to SEMI Standard F57-0312, the specification for polymer components used in ultrapure water and liquid chemical distribution systems. Higher performance with greater back (outlet) pressure capability. All wetted parts are molded PFA providing chemical resistance suitable for use in high purity, high corrosive chemical handling applications.

Product Image-HECH40850002

Pressure bulbs

Dodavatel: GLASWARENFABRIK KARL HECHT
Popis: simple: with 2 valves – made of soft PVC (cadmium-free)
double: with valve - made of soft PVC (cadmium-free), ball in the net made of latex

Product Image-620-1844

Záznamníky teploty a vlhkosti, testo 175 a 176

Dodavatel: Testo
Popis: Záznamníky testo 175 jsou multifunkční kompaktní záznamníky pro měření teploty a vlhkosti. Záznamníky testo 176 jsou robustní a pevné záznamníky vhodné pro náročné aplikace.

Image Unavailable-BOSSBS-6634R-CY3

Anti-XPC Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-6634R-CY3)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-HRP

Anti-XPC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-6634R-HRP)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-MMMA7100260622

Filters, DT

Katalogové číslo: (MMMA7100260622)
Dodavatel: 3M
Popis: For effective protection against a range of particulates, gases, and vapours, or combination hazards, use 3M™ filters DT series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
Měrná jednotka: 1 * 10 KS
Image Unavailable-181-0362

Scroll pump, XDS series

Katalogové číslo: (181-0362)
Dodavatel: EDWARDS HIGH VACUUM METTLER
Popis: These XDS series pumps are completely oil free, dry scroll and improved on their pumping speeds, combined with lower ultimate pressures, lower power consumption and lower noise. Gas ballast allows for pumping of condensable vapours including water, solvents, dilute acids and bases. It also feature the latest in tip seal technology giving significantly longer life between tip seal changes. Comes with integrated inverter drive with auto sensing voltage input delivers optimised pumping performance. The pumps are completely field serviceable.
Měrná jednotka: 1 * 1 KS
Product Image-28466.230

Molekulové síto A4, (0,4 nm, 4 Å), beads, GPR RECTAPUR® 1.6 - 2.5 mm

Dodavatel: VWR Chemicals
Popis: VWR® 4Å Molecular Sieve is a widely used adsorbent for many different applications. It exhibits high water adsorption capacity at low partial pressures and at temperatures up to 100°C. This molecular sieve is commonly used for drying of organic liquids (solvents, oils, gasolinea and other saturated hydrocarbons, air, liquid gases (propane, butane), as well as noble and other gases (H2, N2, He, Ar, etc.).

Bezpečnostní list Certifikáty

Product Image-BRDY148658

Labels for BradyJet J5000 lab printer

Dodavatel: Brady
Popis: This indoor marking film is an aqueous, inkjet printable, flexible, matte finish, pressure sensitive adhesive product that is designed to be used with the BradyJet™ J5000 colour label printer.

Image Unavailable-MMMADT-1135E

Particulate Filter, DT

Katalogové číslo: (MMMADT-1135E)
Dodavatel: 3M
Popis: For effective protection against a range of particulates, gases and vapours or combination hazards, use 3M™ filters DT-Series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
Měrná jednotka: 1 * 10 KS
Image Unavailable-PRSI90-361

Recombinant Zmp1 M. tuberculosis (from E. coli)

Katalogové číslo: (PRSI90-361)
Dodavatel: ProSci Inc.
Popis: M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.
Měrná jednotka: 1 * 50 µG
Image Unavailable-2879925-U

Inlet liners, FocusLiner™, Supelco®

Dodavatel: Merck
Popis: FocusLiner™ inlet liners are designed with wool plug to promote the rapid vaporisation of the entire sample, minimise mass discrimination, and prevent non-volatile material from entering the column. It incorporates a unique design to prevent the shifting of the wool plug during repeated injections or sudden inlet pressure changes. These liners are suitable for Agilent, Perkinelmer, Shimadzu, Finnigan, Varian and Thermo scientific equipped with split/splitless inlets.

Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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