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Product Image-THBRSV603-500-LSB

Wireless monitoring systems, Smart-Vue

Dodavatel: Thermo Fisher Scientific
Popis: Ambient measurements or monitoring of laboratory equipment.

Product Image-620-2632

VWR® Traceable®, USB data logging barometer,

Katalogové číslo: (620-2632)
Dodavatel: VWR Collection
Popis: The VWR® Traceable® memory loc, USB, data logging barometer simultaneously monitors barometric pressure, temperature and humidity. This device can be used in 21 CFR 11 environments.
Měrná jednotka: 1 * 1 KS

Nové řešení transparentnosti pro evropské zákazníky

Všimli jste si naší nově zlepšené viditelnosti rozmístění zásob u pokladny?

Zjistěte více

Zlepšení rozmístění zásob

Image Unavailable-BOSSBS-6634R-A488

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-6634R-A488)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-CY7

Anti-XPC Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-6634R-CY7)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Product Image-VACU20636155

Vacuum gauge set DCP 3000 + VSP 3000

Dodavatel: VACUUBRAND
Popis: The DCP 3000 is an outstanding vacuum gauge with large illuminated display. The brand new VSP 3000 vacuum sensor is based on thermal conductivity (Pirani) and offers a wide measurement range from atmospheric pressure down to 10 to 3 mbar. The wetted parts are made of chemically resistant plastics (PBT, PUR) and alumina ceramics. It features a much better chemical resistance and ruggedness than conventional Pirani sensors with their fragile metallic spiral-wound filament. Simultaneous connection of up to eight vacuum sensors allows flexible measuring on the spot. The DCP 3000 communicates with external components via the VACUU·BUS® digital bus system. It is characterised by fully automatic configuration, unified plug connections and cable lengths of up to 30 m. In addition the DCP 3000 offers relative pressure measurements (VSK 3000 as reference) and a data logger feature for up to 32000 data values.

Environmentally Preferable

Image Unavailable-BOSSBS-6634R-CY5.5

Anti-XPC Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-6634R-CY5.5)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A555

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-6634R-A555)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Product Image-GRSG605919

Oxygen meter, handheld, GMH 3692

Katalogové číslo: (GRSG605919)
Dodavatel: Greisinger
Popis: Compact meter for measuring oxygen in air and gas mixtures either as partial pressure or as concentration in %vol. For the measuring an external sensor has to be connected to the MINI-DIN socket. Suitable for a wide range of applications, such as oxygen monitoring in breeding chambers for cell cultures, in respirators, incubators and in air conditioning systems.
Měrná jednotka: 1 * 1 KS
Image Unavailable-BOSSBS-6634R-A680

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-6634R-A680)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Product Image-DUEH2.00.081

Ventilation accessories for extraction systems

Dodavatel: DUPERTHAL
Popis: <B>Exhaust air monitor optional with ventilator: </B>Easy ventilation and monitoring of the venting system for safety cabinets. A sensor monitors the air flow speed/stream and gives a visual or audible signal if the value drops below the set-point value. The complete exhaust monitoring unit is supplied pre-assembled (ready to plug in) and is placed directly on the cabinet. The set-point value for the air stream flow rate is preset in the factory and can be individually adjusted by the pressure difference socket. In addition to the volumetric flow rate the power supply is also monitored. The system includes two floating contacts (24 V/2 A) for signal transmission to an external control room. Internal storage accumulator supplies the monitoring systems for 4 hours in the event of a power failure, display with easy fault indication and enables permanent monitoring according to DIN EN 1946-7. The housing is made from powder-coated sheet steel, silver pearl glimmer.

Image Unavailable-BOSSBS-6634R-A750

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-6634R-A750)
Dodavatel: Bioss
Popis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Měrná jednotka: 1 * 100 µl
Product Image-HICHHI-583

Avantor® Hichrom, Inlet Solvent Filters

Dodavatel: Avantor
Popis: These solvent inlet filters are used at the low pressure inlet side of the pump to help protect check valves, injector and column from particulate contamination from the eluent.

Product Image-181-0309

VWR® VCP 80/VCP 130 Vacuum/Pressure Pumps

Dodavatel: VWR Collection
Popis: Jednotky VCP 80 a VCP 130 mohou být použity jako účinná vakuová a tlaková čerpadla. Čerpadla jsou vhodná k tvorbě vakua v aplikacích, kde není vyžadována odolnost proti korozi. Čerpadla mohou být použita pro vakuovou filtraci vodných roztoků nebo vodních výparů včetně pufrů, ale nedoporučují se pro čerpání kyselých, zásaditých nebo organických výparů. Tato vakuová / tlaková čerpadla řady VWR® Collection mohou pracovat nepřetržitě a bez potřeby obsluhy, mají dva manometry s analogovým ukazatelem pro nastavení a snadné sledování požadované úrovně vakua nebo tlaku.

Product Image-391-0649

Pierce™ Sealing Tape for 96-Well Microplates

Katalogové číslo: (391-0649)
Dodavatel: Thermo Fisher Scientific
Popis: Microplate sealing tape consisting of pre-cut, pressure-sensitive sheets for sealing the surface of standard 96-well or 384-well microplates during incubation steps.
Měrná jednotka: 1 * 100 KS
Product Image-731-0452

Adhesive qPCR film seals, QuickSeal qPCR Crystal™

Dodavatel: iST Scientific Ltd
Popis: Clear, non-tacky, pressure sensitive film for qPCR plates (96- or 384-well) and situations where fluorescence is experienced.

Product Image-731-0750

Sealing tape, light blocking, non-fluorescent, Nunc™

Katalogové číslo: (731-0750)
Dodavatel: Thermo Fisher Scientific
Popis: Vinyl film with pressure sensitive acrylate adhesive. For application to plate top or bottom, to protect light sensitive samples.
Měrná jednotka: 1 * 50 KS

Environmentally Preferable


Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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