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Image Unavailable-BOSSBS-13494R-FITC

Anti-GOT1L1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-13494R-FITC)
Dodavatel: Bioss
Popis: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Měrná jednotka: 1 * 100 µl
Product Image-F-140WH

Direct PCR kits

Dodavatel: FINNZYMES REAGENTS
Popis: Direct PCR Kits save time and cost by allowing amplification of DNA directly from the source material. Direct PCR is based on Thermo Scientific Phire® Hot Start II DNA Polymerase and Phusion® Hot Start II High-Fidelity DNA Polymerase. These fusion enzymes are exceptionally fast, robust and highly tolerant of many PCR inhibitors present in unpurified sample material. This allows reliable amplification in challenging conditions where conventional DNA polymerases are completely inhibited.

Product Image-ANTIA79454-96

Mouse Insulin degrading enzyme/IDE ELISA Kit

Katalogové číslo: (ANTIA79454-96)
Dodavatel: ANTIBODIES.COM
Popis: Mouse Insulin degrading enzyme/IDE ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Insulin degrading enzyme/IDE in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

New Product


Image Unavailable-NOVUNB110-60930H

Anti-Gastric Lipase Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (NOVUNB110-60930H)
Dodavatel: Novus Biologicals
Popis: Anti-Gastric Lipase Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Měrná jednotka: 1 * 0,1 mL
Image Unavailable-BOSSBS-8589R-CY5.5

Anti-TG2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-8589R-CY5.5)
Dodavatel: Bioss
Popis: Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-8589R-CY7

Anti-TG2 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-8589R-CY7)
Dodavatel: Bioss
Popis: Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
Měrná jednotka: 1 * 100 µl
Image Unavailable-PRSI92-212

Human recombinant MGMT (from E. coli)

Katalogové číslo: (PRSI92-212)
Dodavatel: ProSci Inc.
Popis: MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyses the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-methyl-L-cysteine.
Měrná jednotka: 1 * 50 µG
Product Image-ANTIA303899-96

Creatinine ELISA Kit

Katalogové číslo: (ANTIA303899-96)
Dodavatel: ANTIBODIES.COM
Popis: Creatinine ELISA kit is a enzyme catalysis Enzyme-Linked Immunosorbent Assay designed for the <i><i>in vitro</i></i> quantitative determination of Creatinine in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

New Product


Product Image-ANTIA303887-96

Heme ELISA Kit

Katalogové číslo: (ANTIA303887-96)
Dodavatel: ANTIBODIES.COM
Popis: Heme ELISA kit is a enzyme catalysis Enzyme-Linked Immunosorbent Assay designed for the in vitro quantitative determination of Heme in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

New Product


Product Image-568-0457

Capillary columns, BPX1

Dodavatel: Trajan Scientific and Medical
Popis: These columns are specifically designed for high temperature hydrocarbon analysis. Ideal for simulated distillation.

Image Unavailable-BOSSBS-1972R-A350

Anti-LCAT Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-1972R-A350)
Dodavatel: Bioss
Popis: Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1972R-A680

Anti-LCAT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-1972R-A680)
Dodavatel: Bioss
Popis: Central enzyme in the extracellular metabolism of plasma lipoproteins. synthesised mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodelling high-density lipoprotein particles into their spherical forms.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13494R-HRP

Anti-GOT1L1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-13494R-HRP)
Dodavatel: Bioss
Popis: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13494R-CY5

Anti-GOT1L1 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-13494R-CY5)
Dodavatel: Bioss
Popis: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ABCAAB223846-20UL

Anti-Gastric Mucin/MUC-6 Rabbit Monoclonal Antibody [clone: EPR20623]

Dodavatel: Abcam
Popis: Anti-Gastric Mucin/MUC-6 Rabbit Monoclonal Antibody [clone: EPR20623]

New Product

Image Unavailable-BOSSBS-1922R-A647

Anti-TRF2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-1922R-A647)
Dodavatel: Bioss
Popis: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Together with DCLRE1B/Apollo, plays a key role in telomeric loop (T loop) formation by generating 3' single-stranded overhang at the leading end telomeres: T loops have been proposed to protect chromosome ends from degradation and repair. Required both to recruit DCLRE1B/Apollo to telomeres and activate the exonuclease activity of DCLRE1B/Apollo. Preferentially binds to positive supercoiled DNA. Together with DCLRE1B/Apollo, required to control the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Recruits TERF2IP/RAP1 to telomeres, thereby participating in to repressing homology-directed repair (HDR), which can affect telomere length.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
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Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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