Hledali jste: Role+zásobní

Katalogové číslo: (BOSSBS-9468R-CY5.5)

Dodavatel: Bioss

Popis: Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0018R-A350)

Dodavatel: Bioss

Popis: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0018R-A750)

Dodavatel: Bioss

Popis: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0018R-CY5.5)

Dodavatel: Bioss

Popis: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2487R-A680)

Dodavatel: Bioss

Popis: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3054R-CY7)

Dodavatel: Bioss

Popis: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2740R-A680)

Dodavatel: Bioss

Popis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalises to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalises to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7112R-A680)

Dodavatel: Bioss

Popis: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganisation of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralisation and bone homeostasis (By similarity). Plays a role in responses to oxidised 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3573R-A750)

Dodavatel: Bioss

Popis: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-2491R-CY5)

Dodavatel: Bioss

Popis: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4910R-FITC)

Dodavatel: Bioss

Popis: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7077R-A555)

Dodavatel: Bioss

Popis: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7077R-HRP)

Dodavatel: Bioss

Popis: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5123R-A555)

Dodavatel: Bioss

Popis: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3851R-A350)

Dodavatel: Bioss

Popis: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3851R-HRP)

Dodavatel: Bioss

Popis: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Měrná jednotka: 1 * 100 µl

Akce