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Popis: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Katalogové číslo: BOSSBS-4599R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Katalogové číslo: BOSSBS-0412R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Katalogové číslo: BOSSBS-0412R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Katalogové číslo: BOSSBS-4605R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Fmoc-Lys(Tfa)-OH
Katalogové číslo: APOSPC27880-25G
Měrná jednotka: 1 * 25 g
Dodavatel: Apollo Scientific


Popis: The 3M™ Peltor™ WS™ LiteCom Pro III Headset features an integrated, programmable analog/digital two-way radio, Bluetooth® Multipoint connectivity, noise-cancelling microphone, and level-dependent function for ambient listening. The headset not only helps protect against hazardous noise, but also makes it easy to communicate in noisy environments and maintain situational awareness.
Katalogové číslo: 111-2496
Měrná jednotka: 1 * 1 KS
Dodavatel: 3M


Popis: Kyselina trifluoroctová ≥99.9% for peptide synthesis
Katalogové číslo: 84578.290
Měrná jednotka: 1 * 1 L
Dodavatel: VWR Chemicals

Popis: Kyselina trifluoroctová ≥99.9%, HiPerSolv CHROMANORM® for LC-MS
Katalogové číslo: 84868.180
Měrná jednotka: 1 * 100 mL
Dodavatel: VWR Chemicals

Popis: Z-L-Lys(Tfa)-OH 95%
Katalogové číslo: APOSPC1597-25G
Měrná jednotka: 1 * 25 g
Dodavatel: Apollo Scientific


Popis: Adaptér (380 V na 230 V) , Určeno pro: -
Katalogové číslo: 481-0863
Měrná jednotka: 1 * 1 KS
Dodavatel: TUTTNAUER


Popis: Gradient tested for HPLC Peptide and Protein Analysis
Katalogové číslo: 9470.0010
Měrná jednotka: 1 * 10 Vial
Dodavatel: Avantor

Popis: SPECTRONORM solvents have extensive specifications to meet the highly demanding requirements of UV applications.
Katalogové číslo: 85930.150
Měrná jednotka: 1 * 25 mL
Dodavatel: VWR Chemicals

Popis: Tube removal tool for TFT-80.2 rotor, Pro: Ultracentrifuge rotors
Katalogové číslo: SORV52177
Měrná jednotka: 1 * 1 KS
Dodavatel: SORVALL


Popis: Kyselina trifluoroctová, BAKER ANALYZED® for LC-MS, J.T.Baker®
Katalogové číslo: 9810.0002AM
Měrná jednotka: 1 * 2 mL
Dodavatel: Avantor

Popis: Micro collection accessory, KFK312, extender for BD Microtainer® with BD Microgard™ closure, to increase the length to 75mm, BD Microtainer®
Katalogové číslo: BDAM368933
Měrná jednotka: 1 * 200 KS
Dodavatel: BD Medical


Popis: Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, alpha1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
Katalogové číslo: PRSI91-351
Měrná jednotka: 1 * 50 µG
Dodavatel: ProSci Inc.


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