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Katalogové číslo: (516-7596)

Dodavatel: Cytiva (Formerly Pall Lab)

Popis: Podstavec pro filtrační nálevkul, bez podpory, Pro filtr Ø: 47 mm

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (USBIZ0300-10E)

Dodavatel: US Biological

Popis: Anti-ZAP70 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 5K146]

Měrná jednotka: 1 * 25 µG

Akce

Katalogové číslo: (USBIZ0300-01D)

Dodavatel: US Biological

Popis: Anti-ZAP70 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (USBIZ0300-20)

Dodavatel: US Biological

Popis: Anti-ZAP70 Rabbit Polyclonal Antibody

Měrná jednotka: 1 * 10 KS

Akce

Katalogové číslo: (BOSSBS-3089R-HRP)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3089R-A647)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3089R-CY5)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (466-2709)

Dodavatel: Thermo Scientific

Popis: Navíc police a podpěry pro VT 6025

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (BOSSBS-3089R-FITC)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3089R-A350)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3089R-A555)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3089R-CY3)

Dodavatel: Bioss

Popis: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13660R)

Dodavatel: Bioss

Popis: SLA2 is a 261 amino acid protein that exists as four alternatively spliced isoforms which localize to either the cytoplasm or to the cell membrane and contain one SH2 domain and one SH3 domain. Expressed predominately in tissues of the immune system, including thymus, spleen and lymph nodes, SLA2 functions as an adaptor protein that negatively regulates T-cell receptor (TCR) signaling and may inhibit T-cell activation. SLA2 interacts with Zap-70 and is subject to post-translational phosphorylation. The gene encoding SLA2 maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-10522R)

Dodavatel: Bioss

Popis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12630R-A488)

Dodavatel: Bioss

Popis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12630R-A555)

Dodavatel: Bioss

Popis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

Měrná jednotka: 1 * 100 µl

Akce