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Popis: (2S,4S)-4-Fluoropyrrolidine-2-carboxamide hydrochloride 98%
Katalogové číslo: H27235.06
Měrná jednotka: 1 * 5 g
Dodavatel: Thermo Fisher Scientific

Popis: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
Katalogové číslo: BOSSBS-2044R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Sturdy and comfortable anti-static safety ankle boot made from water resistant leather upper, soft padded collar and padded dust tongue and a dual-density, self-cleaning and slip-resistant PUR sole (4,5 mm, heat resistant to +120 °C, oil and petrol resistant, silicone-free).
Katalogové číslo: 114-7066
Měrná jednotka: 1 * 1 PÁR
Dodavatel: UVEX


Popis: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Katalogové číslo: BOSSBS-5809R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Anti-slip ESD safety shoes made from hydrophobised nubuck leather and hydrophobised textile upper, a full padded bellows tongue plus a slip resistant, dual-density TPU/PU sole (Dimension Pro).
Katalogové číslo: ELTN72721/37
Měrná jednotka: 1 * 1 PÁR
Dodavatel: ELTEN

Environmentally Preferable


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0058R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0059R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0059R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0058R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0059R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0058R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Katalogové číslo: BNC400956-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Katalogové číslo: BOSSBS-7685R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Katalogové číslo: BOSSBS-1346R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Katalogové číslo: BOSSBS-0059R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Process a range of general-purpose applications including cell culture, microplate, bioproduction, blood separation, and microbiology with the Thermo Scientific™ Multifuge™ X4 Pro centrifuge series featuring new touch screen technology, making daily tasks easier.
Katalogové číslo: 521-2724
Měrná jednotka: 1 * 1 KS
Dodavatel: Thermo Scientific


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