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Image Unavailable-BOSSBS-9097R-CY5

Anti-ANKS1B Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-9097R-CY5)
Dodavatel: Bioss
Popis: The β-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer’s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7674R-A555

Anti-TMEM123 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-7674R-A555)
Dodavatel: Bioss
Popis: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7674R-CY5

Anti-TMEM123 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-7674R-CY5)
Dodavatel: Bioss
Popis: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5424R-A555

Anti-TAB3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-5424R-A555)
Dodavatel: Bioss
Popis: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5424R-HRP

Anti-TAB3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-5424R-HRP)
Dodavatel: Bioss
Popis: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7613R-CY5.5

Anti-RNF144B Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-7613R-CY5.5)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7613R-CY3

Anti-RNF144B Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-7613R-CY3)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7613R

Anti-RNF144B Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-7613R)
Dodavatel: Bioss
Popis: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Měrná jednotka: 1 * 100 µl
Product Image-ANTIA74954-96

Human Pro-Adrenomedullin/Pro-ADM ELISA Kit

Katalogové číslo: (ANTIA74954-96)
Dodavatel: ANTIBODIES.COM
Popis: Human Pro-Adrenomedullin/Pro-ADM ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Pro-Adrenomedullin/Pro-ADM in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

New Product


Product Image-ANTIA74517-96

Human Pro-IL-1 beta ELISA Kit

Katalogové číslo: (ANTIA74517-96)
Dodavatel: ANTIBODIES.COM
Popis: Human Pro-IL-1 beta ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Pro-IL-1 beta in serum, plasma, tissue homogenates, and other biological fluids.
Měrná jednotka: 1 * 96 Tests

New Product


Image Unavailable-BIRBORB98860-100

Recombinant Pro-GRP Ag

Katalogové číslo: (BIRBORB98860-100)
Dodavatel: Biorbyt
Popis: Recombinant Pro-GRP Ag
Měrná jednotka: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-PRSI36-182

Anti-CASP4 Rat Monoclonal Antibody [clone: 8A5]

Katalogové číslo: (PRSI36-182)
Dodavatel: ProSci Inc.
Popis: Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
Měrná jednotka: 1 * 100 µG
Image Unavailable-ENZOBMLP1450001

Cathepsin D & E substrate (fluorogenic)

Katalogové číslo: (ENZOBMLP1450001)
Dodavatel: ENZO LIFE SCIENCES
Popis: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
Měrná jednotka: 1 * 1 mg
Image Unavailable-BOSSBS-11043R-CY5

Anti-BEST4 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-11043R-CY5)
Dodavatel: Bioss
Popis: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2899R-HRP

Anti-FOLH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-2899R-HRP)
Dodavatel: Bioss
Popis: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3354R-HRP

Anti-PIN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-3354R-HRP)
Dodavatel: Bioss
Popis: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
Měrná jednotka: 1 * 100 µl
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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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