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Popis: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Katalogové číslo: BOSSBS-5899R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: A range of different stainless steel accessories for use with JB Academy, JB Nova, SUB Aqua Pro, (also previous models: SUB Aqua Plus, JB Aqua Plus and SBB Aqua Plus baths).
Katalogové číslo: 462-0187
Měrná jednotka: 1 * 1 KS
Dodavatel: GRANT INSTRUMENTS


Popis: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
Katalogové číslo: BOSSBS-6795R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY >[Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY >NPY (2-36) >[Ile-31, Gln-34] PP and PYY (3-36) >PP >NPY free acid.
Katalogové číslo: BOSSBS-1070R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY >NPY >PYY (3-36) >NPY (2-36) >[Ile-31, Gln-34] PP >[Leu-31, Pro-34] NPY >PP, [Pro-34] PYY and NPY free acid.
Katalogové číslo: BOSSBS-0937R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY >NPY >PYY (3-36) >NPY (2-36) >[Ile-31, Gln-34] PP >[Leu-31, Pro-34] NPY >PP, [Pro-34] PYY and NPY free acid.
Katalogové číslo: BOSSBS-0937R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: PCSK4 is a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.
Katalogové číslo: BOSSBS-15501R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Automatic capillary viscometer
Katalogové číslo: SCOI285420852
Měrná jednotka: 1 * 10 KS
Dodavatel: SI Analytics


Popis: Anti-Pro-Collagen III alpha 1 Rabbit Recombinant Multiclonal Antibody [clone: RM1028]
Katalogové číslo: ABCAAB283725-100
Měrná jednotka: 1 * 100 µG
Dodavatel: Abcam


Popis: Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Also known as Appetite regulating hormone; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524. Sequence notes: Gly-Ser-Ser-Phe-Leu-Ser-Pro- Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu- Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg (mo, rat).
Katalogové číslo: BOSSBS-1375R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50% of gliomas.
Katalogové číslo: BOSSBS-0423R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50% of gliomas.
Katalogové číslo: BOSSBS-0423R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Anti-pro Caspase-3 Rabbit Monoclonal Antibody [clone: E61] (Alexa Fluor® 488)
Katalogové číslo: ABCAAB307610-10
Měrná jednotka: 1 * 10 µl
Dodavatel: Abcam


Popis: Target of p53/TP53 with pro-apoptotic function.
Katalogové číslo: BOSSBS-7600R-CY7
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: ESD safety shoe is made from hydrophobised microfibre/hydrophobised textile upper and a TPU/PU sole (Wellmaxx Trainers Power). Sole core made of Infinergy® by BASF
Katalogové číslo: ELTN721331/37
Měrná jednotka: 1 * 1 PÁR
Dodavatel: ELTEN

Environmentally Preferable New Product


Popis: D-β-Proline 97%
Katalogové číslo: APOSOR309146-5G
Měrná jednotka: 1 * 5 g
Dodavatel: Apollo Scientific