Hledali jste: Methyl-beta-cyclodextrin+(mixture+of+several+Methylated)

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Anti-CARM1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-4098R)

Dodavatel: Bioss

Popis: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-PRMT4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-6144R-A750)

Dodavatel: Bioss

Popis: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Soluble carboxymethyl-beta-cyclodextrin polymer

Dodavatel: Apollo Scientific

Popis: Soluble carboxymethyl-beta-cyclodextrin polymer

VWR® PESTINORM®, GC Multiresidue Pesticide Standard (Mix 2) - 40 components, CRM

Katalogové číslo: (91114.001)

Dodavatel: VWR Chemicals

Popis: A standard mixture, typically used for food testing, containing the following components: 100 ug/ml each of Aldrin [CAS:309-00-2] ; Alpha-HCH [CAS:319-84-6] ; Beta-HCH [CAS:319-85-7] ; Delta-HCH [CAS:319-86-8] ; Gamma-HCH (Lindane) [CAS:58-89-9] ; Chlorbenside [CAS:103-17-3] ; cis-Chlordane [CAS:5103-71-9] ; trans-Chlordane [CAS:5103-74-2] ; Chlorfenson [CAS:80-33-1] ; Chloroneb [CAS:2675-77-6] ; 2,4'-DDD [CAS:53-19-0] ; 4,4'-DDD (TDE) [CAS:72-54-8] ; 2,4'-DDE [CAS:3424-82-6] ; 4,4'-DDE [CAS:72-55-9] ; 2,4'-DDT [CAS:789-02-6] ; 4,4'-DDT [CAS:50-29-3] ; 4,4'-Dichlorobenzophenone [CAS:90-98-2] ; Dieldrin [CAS:60-57-1] ; Endosulfan-alpha [CAS:959-98-8] ; Endosulfan-beta [CAS:33213-65-9] ; Endosulfan-ether [CAS:3369-52-6] ; Endosulfan-total (sulfate) [CAS:1031-07-8] ; Endrin [CAS:72-20-8] ; Endrin aldehyde [CAS:7421-93-4] ; Endrin ketone [CAS:53494-70-5] ; Perthane [CAS:72-56-0] ; Fenson [CAS:80-38-6] ; Heptachlor [CAS:76-44-8] ; Heptachlor-exo-epoxide [CAS:1024-57-3] ; Hexachlorobenzene [CAS:118-74-1] ; Isodrin [CAS:465-73-6] ; o,p'-Methoxychlor-olefin [CAS:30667-99-3] ; 4,4'-Methoxychlor olefin [CAS:2132-70-9] ; Mirex [CAS:2385-85-5] ; cis-Nonachlor [CAS:5103-73-1] ; trans-Nonachlor [CAS:39765-80-5] ; Pentachloroanisole [CAS:1825-21-4] ; Pentachlorobenzene [CAS:608-93-5] ; Methyl-pentachlorophenyl sulfide [CAS:1825-19-0] ; Tetradifon [CAS:116-29-0] in Toluene

Měrná jednotka: 1 * 1 mL

Bezpečnostní list Certifikáty Akce

N/A Each

β-Cyclodextrine

Dodavatel: Apollo Scientific

Popis: β-Cyclodextrine

Anti-CARM1 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-4098R-CY3)

Dodavatel: Bioss

Měrná jednotka: 1 * 100 µl

Akce

N/A Each

Anti-PRMT4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-6144R-A680)

Dodavatel: Bioss

Popis: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.

Měrná jednotka: 1 * 100 µl

Akce