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Product Image-RETS70.760.0001

Fluid bed dryer, TG 200

Popis: The TG 200 fluid bed dryer is used in quality control, sample preparation and research departments. It allows the gentle drying of organic, inorganic, chemical or pharmaceutical bulk materials without localised overheating.
Katalogové číslo: RETS70.760.0001
Měrná jednotka: 1 * 1 KS
Dodavatel: Retsch GmbH
Product Image-733-2553

VWR®, TEMPase Hot Start DNA polymerase

Popis: VWR® TEMPase Hot Start DNA Polymerases are highly stable polymerases, featuring higher specificity, superior sensitivity and greater yields compared to standard DNA polymerases. These features make them well suited for the detection of low abundance targets. Other uses include screening, amplification of GC-rich sequences, multiplex PCR, direct PCR and qPCR. A glycerol-free TEMPase Hot Start DNA Polymerase is also available for automation and freeze drying.
Katalogové číslo: 733-2553
Měrná jednotka: 1 * 2.500 Tests
Dodavatel: VWR Chemicals
Image Unavailable-BOSSBS-3968R-A750

Anti-AMPK gamma 3/PRKAG3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Popis: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Katalogové číslo: BOSSBS-3968R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Product Image-25-050-CI

Corning® Trypsin

Popis: 0,25% Trypsin in HBSS (Hank’s Balanced Salt Solution) without calcium and magnesium.
Katalogové číslo: 25-050-CI
Měrná jednotka: 1 * 6 KS
Dodavatel: Corning

Certifikáty


Image Unavailable-BOSSBS-5164R-CY5.5

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Cy5.5®)

Popis: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Katalogové číslo: BOSSBS-5164R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-PRSI33-206

Anti-TFF1 Mouse Monoclonal Antibody [clone: GE2]

Popis: This antibody recognises a polypeptide of ~6.5 kDa, identified as Estrogen Inducible Protein pS2. The antibody's epitope is localized between amino acids 57-84. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. Estrogen Inducible Protein pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for estrogen inducible protein pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. It is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that estrogen inducible protein pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
Katalogové číslo: PRSI33-206
Měrná jednotka: 1 * 100 µG
Dodavatel: ProSci Inc.

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Image Unavailable-BOSSBS-5164R-A350

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Popis: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Katalogové číslo: BOSSBS-5164R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-5164R-A488

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Popis: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Katalogové číslo: BOSSBS-5164R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-5164R-A750

Anti-ETS1 associated protein 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Popis: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. catalyses the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. hydrolyses 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Katalogové číslo: BOSSBS-5164R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Product Image-786-430

SAM Methyltransferase assay, SAM510™

Popis: SAM510™ assay is a continuous enzyme coupled assay that can continuously monitor SAM-dependent methyltransferases without the use of radioactive labels or endpoint measurements.
Katalogové číslo: 786-430
Měrná jednotka: 1 * 100 Assays
Dodavatel: G-Biosciences
Product Image-25-051-CI

Corning® Trypsin

Popis: 0,05% Trypsin/0,53 mM EDTA in HBSS (Hank’s Balanced Salt Solution) with sodium bicarbonate, without calcium and magnesium.
Katalogové číslo: 25-051-CI
Měrná jednotka: 1 * 6 KS
Dodavatel: Corning

Certifikáty


Image Unavailable-BOSSBS-3968R-A680

Anti-AMPK gamma 3/PRKAG3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Popis: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Katalogové číslo: BOSSBS-3968R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Image Unavailable-BOSSBS-3807R-CY5

Anti-PLAA Rabbit Polyclonal Antibody (Cy5®)

Popis: Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha.
Katalogové číslo: BOSSBS-3807R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
Product Image-25-053-CI

Corning® Trypsin

Popis: 0,05% Trypsin/0,53 mM EDTA in HBSS (Hank’s Balanced Salt Solution) with sodium bicarbonate, without calcium and magnesium.
Katalogové číslo: 25-053-CI
Měrná jednotka: 1 * 6 KS
Dodavatel: Corning

Bezpečnostní list Certifikáty


Image Unavailable-ICNA08320961

Trichoderma viride cellulase Y-C, MP Biomedicals

Popis: Cellulase Y-C removes cell walls from plant tissues in shorter incubation period without loss of biological activity of the materials.
Katalogové číslo: ICNA08320961
Měrná jednotka: 1 * 10 g
Dodavatel: MP Biomedicals
Image Unavailable-BOSSBS-3807R-CY5.5

Anti-PLAA Rabbit Polyclonal Antibody (Cy5.5®)

Popis: Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha.
Katalogové číslo: BOSSBS-3807R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss
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