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Anti-CD53 Mouse Monoclonal Antibody (CF640R) [clone: 63-5A3]

Dodavatel: Biotium
Popis: Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop V; Code CD53.1). CD53 is expressed on monocytes, and macrophages, granulocytes, dendritic cells, osteoblasts and osteoclasts, NK cells, and on T- and B-cells from every stage of differentiation but is absent from platelets, erythrocytes, and non-haemopoietic cells. CD53 is a member of a family of tetraspan transmembrane proteins, including CD9, CD37, CD63, CD81, and CD82. It associates with integrins, MHC class II molecules, and a tyrosine phosphatase and plays a role in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. Defects of CD53 expression on neutrophils appear to be related with recurrent infectious diseases. Cross-linking CD53 using CD53 antibodies led to cytoplasmic calcium fluxes in B cells, monocytes, and granulocytes and activation of the monocyte oxidative burst.

Image Unavailable-BOSSBS-3717R-A350

Anti-TP73 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalogové číslo: (BOSSBS-3717R-A350)
Dodavatel: Bioss
Popis: P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
Měrná jednotka: 1 * 100 µl
Product Image-MOTIPS3645B201

Stereomikroskopy, ST-30 and ST-36

Dodavatel: MOTIC
Popis: These stereo microscopes are designed for education as well as quality control.

Image Unavailable-BOSSBS-3717R-HRP

Anti-TP73 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-3717R-HRP)
Dodavatel: Bioss
Popis: P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9629R-CY5.5

Anti-C16orf7 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-9629R-CY5.5)
Dodavatel: Bioss
Popis: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Měrná jednotka: 1 * 100 µl
Product Image-HAKATSGPACL10

Accessories for Precision™ general purpose water baths

Dodavatel: THERMO ELECTRON LED
Popis: Unstirred water bath

Product Image-ZEIS4300379052000

Accessories

Katalogové číslo: (ZEIS4300379052000)
Dodavatel: ZEISS
Popis: Accessory for microscopes, Pro: Axiolab 5 MAT, Microscope stand Axiolab 5, TL/RL, 5×HD coded, mechanical stage 75×30 R, R - reflected-light illumination with white LED 10 W
Měrná jednotka: 1 * 1 KS
Image Unavailable-AATB1059

iFluor® 546 maleimide

Katalogové číslo: (AATB1059)
Dodavatel: AAT BIOQUEST
Popis: iFluor® 546 dye might be the brightest fluorophore available that is well excited by the 546 nm laser or LED light sources.
Měrná jednotka: 1 * 1 mg

New Product


Product Image-MOTI1101001704392

Mikroskopy metalurgické, BA310 MET

Dodavatel: MOTIC
Popis: These metallurgical microscopes are designed for viewing opaque materials such as minerals and metals.

Product Image-MOTI1101002404501

Stereo zoom microscopes, SMZ-140 and SMZ-143

Katalogové číslo: (MOTI1101002404501)
Dodavatel: MOTIC
Popis: These digital stereo zoom microscopes are suitable for inspection and assembly applications.
Měrná jednotka: 1 * 1 KS
Product Image-461-3484

Recirculating coolers, FL series

Dodavatel: JULABO GmbH
Popis: Compact, ergonomically designed chillers which have integrated stainless steel tanks with large volumes. Models can be either air or water cooled. Applications include use with rotary evaporators, autoclaves, reaction vessels and for routine laboratory cooling. All units have an LED temperature display for actual/set point integrated into a splash-proof keypad and recessed grips for easy relocation integrated in the housing. A hinged tray serves as a compartment for the operating manual and other documents. The removable venting grid allows for easy cleaning of the condenser. Venting slots are located on the front and back, allowing units to be placed directly next to each other. Models FL2503 to FLW11006 have an early warning function with sensor monitoring to signal if the condenser is dirty, and online diagnostics with 'BlackBox' function.

Environmentally Preferable

Image Unavailable-GEAG03.9202

Butyrometer Waterbath

Katalogové číslo: (GEAG03.9202)
Dodavatel: Gerber Instruments AG
Popis: Waterbath for tempering liquids with continuous microprocessor control for easy operation. Radiator made of stainless steel , incl. ground grid, 7-segment LED display.
Měrná jednotka: 1 * 1 KS

New Product


Image Unavailable-BOSSBS-9629R-A488

Anti-C16orf7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-9629R-A488)
Dodavatel: Bioss
Popis: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9023R-A750

Anti-IQCK Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-9023R-A750)
Dodavatel: Bioss
Popis: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterised by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. alternatively splicing events.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9729R-CY5

Anti-FAM96B Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-9729R-CY5)
Dodavatel: Bioss
Popis: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The FAM96B gene product has been provisionally designated FAM96B pending further characterization.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9729R-CY3

Anti-FAM96B Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-9729R-CY3)
Dodavatel: Bioss
Popis: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The FAM96B gene product has been provisionally designated FAM96B pending further characterization.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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