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MMP-13 inhibitor ≥99% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Potent MMP-13 inhibitor.

New Product

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CL-82198 (MMP-13 inhibitor) ≥98% (by TLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation.

New Product

Image Unavailable-ENZOBMLAK4120001

Matrix Metalloproteinase-13 (MMP-13) colorimetric drug discovery kit

Katalogové číslo: (ENZOBMLAK4120001)
Dodavatel: ENZO LIFE SCIENCES
Popis: A QuantiZyme™ Assay System. The MMP-13 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a thiopeptide as a chromogenic substrate.
Měrná jednotka: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK4130001

Matrix Metalloproteinase-13 (MMP-13) fluorometric drug discovery kit

Katalogové číslo: (ENZOBMLAK4130001)
Dodavatel: ENZO LIFE SCIENCES
Popis: A QuantiZyme™ Assay System. The MMP-13 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
Měrná jednotka: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLP1450001

Cathepsin D & E substrate (fluorogenic)

Katalogové číslo: (ENZOBMLP1450001)
Dodavatel: ENZO LIFE SCIENCES
Popis: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
Měrná jednotka: 1 * 1 mg

New Product


Image Unavailable-ENZOBMLP2350001

ADAM Substrate

Katalogové číslo: (ENZOBMLP2350001)
Dodavatel: ENZO LIFE SCIENCES
Popis: Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
Měrná jednotka: 1 * 1 mg

New Product


Product Image-ENZOBMLP1320500

TACE substrate (fluorogenic)

Katalogové číslo: (ENZOBMLP1320500)
Dodavatel: ENZO LIFE SCIENCES
Popis: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
Měrná jednotka: 1 * 0,5 mg

New Product


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Human recombinant TIMP2 (from cells)

Katalogové číslo: (PRSI91-415)
Dodavatel: ProSci Inc.
Popis: Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Měrná jednotka: 1 * 50 µG
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Mouse recombinant TIMP1

Katalogové číslo: (PRSI92-603)
Dodavatel: ProSci Inc.
Popis: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
Měrná jednotka: 1 * 50 µG
Image Unavailable-PRSI91-412

Human recombinant TIMP1 (from cells)

Katalogové číslo: (PRSI91-412)
Dodavatel: ProSci Inc.
Popis: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
Měrná jednotka: 1 * 50 µG
Image Unavailable-ENZOENZCHM1330001

MMP-​9 inhibitor I ≥97% (by HPLC)

Katalogové číslo: (ENZOENZCHM1330001)
Dodavatel: ENZO LIFE SCIENCES
Popis: Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
Měrná jednotka: 1 * 1 mg

New Product


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MMP-3 inhibitor ≥95% (by HPLC)

Katalogové číslo: (ENZOALX260165M005)
Dodavatel: ENZO LIFE SCIENCES
Popis: Inhibitor of matrix metalloproteinase 3 (MMP-3) (IC50=5µM).
Měrná jednotka: 1 * 5 mg

New Product


Image Unavailable-ENZOBMLAK3080001

MMP inhibitor profiling kit

Katalogové číslo: (ENZOBMLAK3080001)
Dodavatel: ENZO LIFE SCIENCES
Popis: The MMP inhibitor profiling kit, fluorometric RED is a complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes, using a quenched fluorogenic substrate OMNIMMP® RED.
Měrná jednotka: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0160001

MMP Inhibitor profiling kit, fluorometric

Katalogové číslo: (ENZOBMLAK0160001)
Dodavatel: ENZO LIFE SCIENCES
Popis: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a sensitive fluorogenic substrate . Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
Měrná jednotka: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0150001

MMP Inhibitor profiling kit, colorimetric

Katalogové číslo: (ENZOBMLAK0150001)
Dodavatel: ENZO LIFE SCIENCES
Popis: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a chromogenic substrate1,2 detected at 412 nm. Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
Měrná jednotka: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK3010001

MMP Fluorometric drug discovery kits, RED and GREEN

Dodavatel: ENZO LIFE SCIENCES
Popis: The matrix metalloproteinase (MMP) RED and GREEN Drug Discovery Kits are complete assay systems designed to screen MMP inhibitors, using long-wavelength quenched fluorogenic substrates OmniMMP™ RED or Fluorogenic Substrate (GREEN). The assays are performed in a convenient 96-well microplate format, with the compound NNGH also included as a prototypic control inhibitor.

New Product

Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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