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Image Unavailable-BOSSBS-9634R-A750

Anti-IDH1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-9634R-A750)
Dodavatel: Bioss
Popis: The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyses the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ketoglutarate and CO₂ in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ketoglutarate. During this process, either NADH or NADPH is produced along with CO₂. Ca²⁺ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg²⁺. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5015R-CY7

Anti-ACADL Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-5015R-CY7)
Dodavatel: Bioss
Popis: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10150R-CY3

Anti-ACADL Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-10150R-CY3)
Dodavatel: Bioss
Popis: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4192R-CY5.5

Anti-SLC25A20 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-4192R-CY5.5)
Dodavatel: Bioss
Popis: SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4192R-CY7

Anti-SLC25A20 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-4192R-CY7)
Dodavatel: Bioss
Popis: SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1603R-A680

Anti-AARS2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-1603R-A680)
Dodavatel: Bioss
Popis: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9095R-HRP

Anti-AGXT2L2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-9095R-HRP)
Dodavatel: Bioss
Popis: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9095R-A750

Anti-AGXT2L2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-9095R-A750)
Dodavatel: Bioss
Popis: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localises to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9095R-A488

Anti-AGXT2L2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-9095R-A488)
Dodavatel: Bioss
Popis: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10150R-A488

Anti-ACADL Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalogové číslo: (BOSSBS-10150R-A488)
Dodavatel: Bioss
Popis: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
Měrná jednotka: 1 * 100 µl
Image Unavailable-CAYM21880-50

Ricobendazole ≥98%

Dodavatel: Cayman Chemical
Popis: Ricobendazole, also known as albendazole sulfate, is a benzimidazole agent that inhibits tubulin polymerization and is commonly used as an antihelmintic and antiparasitic agent, with IC90 values ranging from 3.8 x 10-2 to <10-4 µg/ml against Encephalitozoon species.

Product Image-BOSSBS-3936R

Anti-SLC27A2 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-3936R)
Dodavatel: Bioss
Popis: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3936R-CY5

Anti-SLC27A2 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-3936R-CY5)
Dodavatel: Bioss
Popis: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0494R-A680

Anti-ETFA Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-0494R-A680)
Dodavatel: Bioss
Popis: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4055R-CY5.5

Anti-PPARA Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-4055R-CY5.5)
Dodavatel: Bioss
Popis: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13048R-A750

Anti-ECH1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-13048R-A750)
Dodavatel: Bioss
Popis: ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Měrná jednotka: 1 * 100 µl
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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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