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IKK Inhibitor VI ≥95%

Dodavatel: Cayman Chemical
Popis: IKK Inhibitor VI ≥95%

Image Unavailable-ENZOBMLEI3430050

SC-514 ≥98% (by TLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: IKK inhibitor

New Product

Celodenní výkon. Každodenní výdrž

Pracujte rychle s kompaktními, výkonnými tiskárnami štítků M510 a M611, které zajišťují velkokapacitní tisk štítků ve vysoké kvalitě s připojením přes Bluetooth nebo Wi-Fi

Další informace

Seznamte se s tiskárnami štítků M510 a M611

Image Unavailable-ENZOBMLP6070500

IKK-NBD peptide

Katalogové číslo: (ENZOBMLP6070500)
Dodavatel: ENZO LIFE SCIENCES
Popis: NF-kappaB inhibitor
Měrná jednotka: 1 * 0,5 mg

New Product


Image Unavailable-ENZOBMLEI3160001

Wedelolactone ≥98% (by TLC)

Katalogové číslo: (ENZOBMLEI3160001)
Dodavatel: ENZO LIFE SCIENCES
Popis: IKK inhibitor
Měrná jednotka: 1 * 1 mg

New Product


Image Unavailable-ENZOENZCHM1890010

BX-795 ≥97% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Inhibitor of PDK1, TBK1, IKK-ε, IRF3

New Product

Image Unavailable-BOSSBS-3232R-A750

Anti-IKK beta Tyr199 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-3232R-A750)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-A647

Anti-IKBKB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-3232R-A647)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3232R-A555

Anti-IKBKB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-3232R-A555)
Dodavatel: Bioss
Popis: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3228R-A750

Anti-IKK gamma Ser31 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalogové číslo: (BOSSBS-3228R-A750)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3228R-CY5.5

Anti-IKBKG Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-3228R-CY5.5)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3228R-HRP

Anti-IKBKG Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-3228R-HRP)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3228R-FITC

Anti-IKBKG Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-3228R-FITC)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-CY5.5

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-6202R-CY5.5)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R-CY7

Anti-TRAF3IP2 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-6202R-CY7)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6202R

Anti-TRAF3IP2 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-6202R)
Dodavatel: Bioss
Popis: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3228R-A647

Anti-IKBKG Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-3228R-A647)
Dodavatel: Bioss
Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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