Hledali jste: HYSERVE

Katalogové číslo: (BOSSBS-3390R-A750)

Dodavatel: Bioss

Popis: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of foetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organisation and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organisation and the transcription profiles of breast tumors to promote growth and metastasis.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: LIOFILCHEM

Popis: Dehydrated culture media in powder available in 100 g, 500 g and 5 kg formats.

Dodavatel: Merck

Popis: Tryptophan broth, Aplikace: Selective media, Selektivní pro: E. coli, Standard: -

Katalogové číslo: (EDVO611)

Dodavatel: EDVOTEK

Popis: LB media, 100 g, Aplikace: Selective media, Selektivní pro: E.coli, Standard: -

Měrná jednotka: 1 * 100 g

Akce

Katalogové číslo: (84958.180)

Dodavatel: VWR Chemicals

Popis: Standardy - vápník, 1000 mg/L, VWR®, Kalcium, Matrice: H₂O, Aplikace: Standardy iontové chromatografie

Měrná jednotka: 1 * 100 mL

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Katalogové číslo: (84959.180)

Dodavatel: VWR Chemicals

Popis: Standardy - cesium, 1000 mg/L, VWR®, Cesium, Matrice: H₂O, Aplikace: Standardy iontové chromatografie

Měrná jednotka: 1 * 100 mL

Bezpečnostní list Certifikáty Akce

Dodavatel: Thermo Fisher Scientific

Popis: Standardy - lithium, 1000 mg/L, Lithium, Matrice: 2% HCl, Aplikace: Standardy AAS

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Katalogové číslo: (ACRO195805000)

Dodavatel: Thermo Fisher Scientific

Popis: Standardy - hliník, 1000 mg/L, Hliník, Matrice: 0,5 M HNO₃, Aplikace: Standardy AAS

Měrná jednotka: 1 * 500 mL

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Katalogové číslo: (85001.180)

Dodavatel: VWR Chemicals

Popis: Standardy aminů, Triethanolamine standard, 1000 mg/L, VWR®, Matrice: H₂O, Aplikace: Standardy iontové chromatografie

Měrná jednotka: 1 * 100 mL

Bezpečnostní list Certifikáty Akce

Katalogové číslo: (85037.180)

Dodavatel: VWR Chemicals

Popis: Osm prvků v 7% roztoku kyseliny dusičné.

Měrná jednotka: 1 * 100 mL

Bezpečnostní list Certifikáty Akce

Dodavatel: VWR Chemicals

Popis: Mikrobiologická kultivační média naplněná v sáčcích jsou ideální pro použití všude tam, kde se používají velká množství vzorků.

Certifikáty

Katalogové číslo: (BOSSBS-3390R-FITC)

Dodavatel: Bioss

Popis: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3390R-A488)

Dodavatel: Bioss

Popis: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: VWR Chemicals

Popis: Standardy - hliník, 1000 mg/l, VWR®, Matrice: 2% HCl, Aplikace: Standardy AAS

Bezpečnostní list Certifikáty

Katalogové číslo: (ACRO196471000)

Dodavatel: Thermo Fisher Scientific

Popis: Standardy - zirkon, 1000 mg/L, Zirconium, Matrice: 5% HF, Aplikace: Standardy AAS

Měrná jednotka: 1 * 100 mL

Bezpečnostní list Akce

Dodavatel: Thermo Fisher Scientific

Popis: Standardy - hliník, 1000 mg/L, Specpure®, Hliník, Matrice: 5% HCl, Aplikace: Standardy AAS

Bezpečnostní list Certifikáty