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Image Unavailable-ENZOALX350108M001

Pseudolaric acid B ≥95%

Katalogové číslo: (ENZOALX350108M001)
Dodavatel: ENZO LIFE SCIENCES
Popis: Activates PPAR alpha and the phospholipase C (PLC) signalling pathway. Stimulates peroxisomal fatty acyl-CoA oxidase activity. These effects can be blocked by staurosporine (Prod. No. ALX-380-014). Exhibits significant cytotoxic activities against numerous tumor cell lines. Binds tubulin. Inhibits angiogenesis. Reduces HIF-1alpha protein levels. Induces apoptosis. Antifungal.
Měrná jednotka: 1 * 1 mg
Image Unavailable-BNUM0515-50

Anti-CD79A Mouse Monoclonal Antibody (Purified, BSA-free) [clone: IGA/515]

Katalogové číslo: (BNUM0515-50)
Dodavatel: Biotium
Popis: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
Měrná jednotka: 1 * 50 µl
Product Image-513-0142

Glass microfibre filters without binder, grade GF/C RTU, Whatman™

Dodavatel: Whatman products (Cytiva)
Popis: These borosilicate glass filters are widely used as total suspended solids filters for applications testing both potable water and waste water.

Product Image-114-8803

ESD safety ankle boots, lace-Up, L10, shadow mid

Dodavatel: ELTEN
Popis: Casual, vintage style, environmental friendly manufactured ESD safety ankle boot made from cowhide leather, a full padded bellows tongue, leather lining and a dual density TPU/PU sole (L10).

Environmentally Preferable

Product Image-390-1336

VWR® INCU-Line® CR PREMIUM Cooled Incubators

Dodavatel: VWR Collection
Popis: These compressor-cooled incubators provide a temperature range between –10 to +100 °C with forced air convection and fan speed control (10 to 100%). Featuring a stainless steel (DIN 1.4301) inner chamber and a powder coated sheet exterior. PREMIUM models have an intuitive menu and user friendly software, USB port with flash drive for data download to USB stick and for uploading programs. They can be connected to Ethernet or Wi-Fi network for remote control from any computer and users can receive notifications about selectable parameters via e-mail.

Product Image-ANSE48-913/10

General purpose gloves, Edge® 48-913

Dodavatel: Ansell
Popis: These ¾ nitrile coated gloves with cotton jersey lining offer good resistance to abrasive materials.

Product Image-MICRAUTOPC-1

Cleanroom autoclave indicator tape

Dodavatel: MICRONOVA
Popis: Saturated crepe paper/synthetic poly isoprene adhesive in plastic core. It is a proven method of positively confirming a completed sterilisation cycle in both gravity discharge and vacuum autoclaves. Green indicator lines change to black when proper levels of steam pressure and temperature have been achieved. After use, the tape removes quickly and completely, leaving minimal residue or staining.

Certifikáty Environmentally Preferable

Image Unavailable-ENZOBMLEI2520005

RG-13022 ≥98% (by TLC)

Katalogové číslo: (ENZOBMLEI2520005)
Dodavatel: ENZO LIFE SCIENCES
Popis: RG-13022 is a non-phenolic tyrphostin analog, which inhibits the EGF receptor (IC50=5 µM) and PDGF receptor tyrosine kinases, and is long-acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=1 µM) as well as tumor growth in vivo. It inhibits both EGF- and PDGF-stimulated DNA synthesis in human glioma cell lines. RG-13022 is non-phenolic and therefore possesses less antioxidant activity than other tyrphostins.
Měrná jednotka: 1 * 5 mg
Image Unavailable-ENZOBMLEI3690025

Dorsomorphin ≥98% (by TLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

Image Unavailable-BNC880828-100

Anti-CD79A Mouse Monoclonal Antibody (CF488A) [clone: JCB117 HM47/A9]

Dodavatel: Biotium
Popis: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Product Image-ELTN7681101/47

ESD safety ankle boots, lace-up, Mason Pro Mid

Dodavatel: ELTEN
Popis: ESD safety ankle boots made from wear resistant breathable cowhide leather with fabric lining, reflective materials, a full padded bellows tongue and a dual density PU/PU sole ERGO-ACTIVE 2.

Environmentally Preferable

Product Image-112-4976

Isolator gloves, AlphaTec® CSM

Dodavatel: Ansell
Popis: These ambidextrous isolator box gloves are made ​​of chlorosulfonated polyethylene (CSM) without an inner lining. They are designed for high resistance against concentrated acids and bases.

Image Unavailable-BOSSBS-7895R-A555

Anti-DBF4 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-7895R-A555)
Dodavatel: Bioss
Popis: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3331R-A647

Anti-PFK2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-3331R-A647)
Dodavatel: Bioss
Popis: 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2,6-bisphosphate. Fructose-2,6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1), which catalyses a key step in the glycoytic pathway. Glycolytic flux is key to tumour growth, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth. Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3331R-FITC

Anti-PFK2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-3331R-FITC)
Dodavatel: Bioss
Popis: 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2,6-bisphosphate. Fructose-2,6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1), which catalyses a key step in the glycoytic pathway. Glycolytic flux is key to tumour growth, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth. Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9447R-CY7

Anti-BMP10 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-9447R-CY7)
Dodavatel: Bioss
Popis: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Měrná jednotka: 1 * 100 µl
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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