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Image Unavailable-PRSI91-305

Human recombinant Complement Factor B (from cells)

Katalogové číslo: (PRSI91-305)
Dodavatel: ProSci Inc.
Popis: Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Měrná jednotka: 1 * 50 µG
Product Image-SHBT100-18-10UG

Human Recombinant PDGF-BB (from E. coli)

Dodavatel: Shenandoah Biotechnology
Popis: Monokine induced by gamma interferon (MIG or CXCL9) is a T cell chemoattractant during neuroinflammatory events. MIG production is stimulated by interferon gamma (IFNɣ) and signals through the chemokine receptor CXCR3.

Image Unavailable-BOSSBS-12157R-CY5

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-12157R-CY5)
Dodavatel: Bioss
Popis: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12157R-CY7

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-12157R-CY7)
Dodavatel: Bioss
Popis: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Měrná jednotka: 1 * 100 µl
Image Unavailable-ANTIA251400-100

Anti-Creatine Kinase BB Mouse Monoclonal Antibody [clone: CPTC-CKB-2]

Katalogové číslo: (ANTIA251400-100)
Dodavatel: ANTIBODIES.COM
Popis: Anti-Creatine Kinase BB Mouse Monoclonal Antibody [clone: CPTC-CKB-2]
Měrná jednotka: 1 * 100 µG

New Product


Product Image-412-0215

Jaw crushers, BB 50

Dodavatel: Retsch GmbH
Popis: The BB 50 is a robust and powerful forced feed crusher that has been specifically designed for rapid but gentle, bench-top sample preparation of hard, brittle and hard-ductile materials in batches. The dust-tight, laboratory instrument is suitable for applications including constructional materials, mineralogy, metallurgy, ceramics and environmental analysis. A convenient operating keypad with digital display and a memory function for gap width setting, facilitates reproducible operation.

Product Image-ANTIA95599-100

Anti-PDGF AB + BB Rabbit Polyclonal Antibody

Katalogové číslo: (ANTIA95599-100)
Dodavatel: ANTIBODIES.COM
Popis: Rabbit polyclonal antibody to PDGF-A for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Měrná jednotka: 1 * 100 µG

New Product


Image Unavailable-BOSSBS-12157R-A555

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-12157R-A555)
Dodavatel: Bioss
Popis: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOADI905682100

Anti-PDGFRB Mouse Monoclonal Antibody [clone: 42G12]

Katalogové číslo: (ENZOADI905682100)
Dodavatel: ENZO LIFE SCIENCES
Popis: Mitogenic platelet derived growth factor (PDGF) signaling is mediated by the PDGF tyrosine kinase receptors PDGFRα and PDGFRβ, which exist as homo- or heterodimer isoforms (αα, ββ, αβ). Secretion of PDGFs and expression of PDGFRs in a broad distribution of cell types contributes to regulation of cellular processes including cell growth, actin reorganization, prevention of apoptosis, and chemotaxis. Structurally, the transmembrane PDGFRs are composed of an N-terminal extracellular domain with five immunoglobulin repeats, and an intracellular domain containing two spaced tyrosine kinase domains. PDGF ligands display preferential affinity to PDGFRα and PDGFRβ, with PDGFRβ activation restricted to binding by PDGF BB and PDGF DD. Growth factor binding initiates receptor dimerization and activates the cytosolic tyrosine kinase domains.
Měrná jednotka: 1 * 100 µG
Image Unavailable-PRSI91-179

Human recombinant PDGF-BB (from E. coli)

Katalogové číslo: (PRSI91-179)
Dodavatel: ProSci Inc.
Popis: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Měrná jednotka: 1 * 50 µG
Image Unavailable-BOSSBS-0964R-CY7

Anti-TRIM32 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-0964R-CY7)
Dodavatel: Bioss
Popis: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0964R

Anti-TRIM32 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-0964R)
Dodavatel: Bioss
Popis: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12157R-FITC

Anti-PDGFA + PDGFB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (BOSSBS-12157R-FITC)
Dodavatel: Bioss
Popis: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0964R-CY3

Anti-TRIM32 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-0964R-CY3)
Dodavatel: Bioss
Popis: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
Měrná jednotka: 1 * 100 µl
Product Image-SHBT200-58-1MG

Mouse Recombinant PDGF-BB (from E. coli)

Dodavatel: Shenandoah Biotechnology
Popis: Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation.

Product Image-ROCK200-401-C12

Anti-BB-H32 Rabbit Polyclonal Antibody

Katalogové číslo: (ROCK200-401-C12)
Dodavatel: Rockland Immunochemicals
Popis: This Protein-A purified antibody has been tested for use in Western blotting and ELISA. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 27.1 kDa in size corresponding to Borrelia burgdorferi p35 Protein by Western blotting.
Měrná jednotka: 1 * 100 µG
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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