Hledali jste: Endotoxinové+Testy

Katalogové číslo: (BOSSBS-9116R-A647)

Dodavatel: Bioss

Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9116R-A680)

Dodavatel: Bioss

Popis: Members of the BAGE gene family encode antigens that are recognised by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9116R-CY5.5)

Dodavatel: Bioss

Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7930R-FITC)

Dodavatel: Bioss

Popis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1899R)

Dodavatel: Bioss

Popis: Strongly expressed in adult testis but weakly expressed in the spleen and thymus. Strongly expressed in round and elongating spermatids, and weakly or not expressed in spermatozoa.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-8193R)

Dodavatel: Bioss

Popis: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-15401R)

Dodavatel: Bioss

Popis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (NLM-06)

Dodavatel: G-Biosciences

Popis: GenLysates™ are total protein tissue and cell lysates that are extracted from the tissue or cell of interest. To inhibit proteolysis, the GenLysates™ are prepared in a lysis buffer containing a complete protease inhibitor cocktail. Each lysate lot is tested by electrophoresis and Western blot analysis.

Měrná jednotka: 1 * 150 µG

Akce

Katalogové číslo: (TB32)

Dodavatel: G-Biosciences

Popis: Single tissue and multiple species blot contains four protein lanes with an identical GenLysate™ tissue lysate from human, mouse and rat species, and a protein marker lane.

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (BOSSBS-15401R-CY3)

Dodavatel: Bioss

Popis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6231R-A488)

Dodavatel: Bioss

Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6231R-FITC)

Dodavatel: Bioss

Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13204R-CY5)

Dodavatel: Bioss

Popis: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11926R-FITC)

Dodavatel: Bioss

Popis: Paraneoplastic neurological disorders (PNDs) are rare syndromes that are caused by, or associated with, an underlying neoplasm. The most common neoplasm among young male patients is testicular cancer, but the leading cause among other patients is lung cancer. Most PNDs are caused by an immune response against onconeural antigens, causing progressive neurological damage. The paraneoplastic antigen MA family contains three known members: MA1, MA2 and MA3. MA1, also designated neuron- and testis-specific protein 1, is a nucleolar protein in normal cells but localizes to the cytoplasm of tumor cells. MA2, also designated onconeuronal antigen MA2, is a nucleolar protein expressed in brain and testis. MA3 is highly expressed in brain and testis and is expressed at low levels in heart, trachea and kidney.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7758R-A680)

Dodavatel: Bioss

Popis: Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7681R-FITC)

Dodavatel: Bioss

Popis: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.Tissue specificity: Ubiquitously expressed with higher levels in testis.

Měrná jednotka: 1 * 100 µl

Akce