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Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Katalogové číslo: BOSSBS-8468R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Katalogové číslo: BOSSBS-5487R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Katalogové číslo: BOSSBS-5487R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Katalogové číslo: BOSSBS-9358R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.
Katalogové číslo: BOSSBS-9351R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Katalogové číslo: BOSSBS-4191R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Katalogové číslo: BOSSBS-5487R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Kyselina L(+)-glutamová 98.5-101.5% USP, Multi-Compendial, J.T.Baker®
Katalogové číslo: 2077-06
Měrná jednotka: 1 * 1 kg
Dodavatel: Avantor

Popis: Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Also known as Appetite regulating hormone; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524. Sequence notes: Gly-Ser-Ser-Phe-Leu-Ser-Pro- Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu- Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg (mo, rat).
Katalogové číslo: BOSSBS-1375R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: FMOC-Glu(EDANS)-OH is a building block for in-sequence peptide Glu labeling by EDANS.
Katalogové číslo: AATB5010
Měrná jednotka: 1 * 1 g
Dodavatel: AAT BIOQUEST


Popis: FMOC-Glu(TQ2)-OH is a building block for in-sequence Lys labeling by Tide Quencher™ 2 (TQ2).
Katalogové číslo: AATB5236
Měrná jednotka: 1 * 100 mg
Dodavatel: AAT BIOQUEST


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Katalogové číslo: BOSSBS-9358R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyses the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.
Katalogové číslo: BOSSBS-0092R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Katalogové číslo: BOSSBS-8468R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Katalogové číslo: BOSSBS-9358R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Katalogové číslo: BOSSBS-8468R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss