Hledali jste: DELTA+T

Katalogové číslo: (BOSSBS-7099R-FITC)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7099R-CY3)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ENZOADI905799100)

Dodavatel: ENZO LIFE SCIENCES

Popis: The opioid receptors delta (DOP, OP1), kappa (KOP, OP2), and mu (MOP, OP3) are members of the seven-transmembrane domain-containing receptor family of G-protein coupled receptors, sharing nearly 60% identity, but varying greatly in the extracellular N-terminus region of the receptors. The delta, kappa and mu-receptors serve as functional receptors for endogenous enkephalin, dynorphin, and beta-endorphin peptide ligands, respectively, mediating their signal via coupling to Gi/o alpha subunits to inhibit adenylyl cyclases and calcium conductance (N- and L-type channels), and to stimulate MAPK activation and potassium conductance. Delta-opioid receptors are highly expressed in the olfactory bulb, neocortex, caudate putamen and nucleus accumbens, with peripheral expression in the gastro-intestinal tract and vas deferens. Delta-opioid receptors function to inhibit neurotransmitter release resulting in a variety of biological effects including analgesia, motor integration, gastro-intestinal motility, olfaction,

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (TEST0563.4409)

Dodavatel: Testo

Popis: Delta P air flow ComboKit 1 equipped with clearly structured measurement menu for volume flow and parallel determination of air velocity, differential pressure, humidity and temperature in ventilation ducts or at ventilation outlets.

Měrná jednotka: 1 * 1 KS

Akce

Katalogové číslo: (BOSSBS-7099R-A488)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-10498R-FITC)

Dodavatel: Bioss

Popis: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0765R-A647)

Dodavatel: Bioss

Popis: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5009R-CY5.5)

Dodavatel: Bioss

Popis: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-0765R-FITC)

Dodavatel: Bioss

Popis: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12095R-A488)

Dodavatel: Bioss

Popis: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12993R-A750)

Dodavatel: Bioss

Popis: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (28553.293)

Dodavatel: VWR Chemicals

Popis: Tetrahydrofuran, Wasser_0,01 99,8 Stabilised, AnalaR NORMAPUR® zA

Měrná jednotka: 1 * 1 L

Bezpečnostní list Certifikáty Akce

Katalogové číslo: (BOSSBS-5009R-CY3)

Dodavatel: Bioss

Popis: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5009R-CY7)

Dodavatel: Bioss

Popis: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6044R)

Dodavatel: Bioss

Popis: Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12095R-A350)

Dodavatel: Bioss

Popis: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Měrná jednotka: 1 * 100 µl

Akce