Hledali jste: DELTA+T

Dodavatel: Thermo Fisher Scientific

Popis: D-Glukono-1,5-lakton 99%

Bezpečnostní list

Katalogové číslo: (BOSSBS-7099R-A555)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7099R-HRP)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7099R-A350)

Dodavatel: Bioss

Popis: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Thermo Fisher Scientific

Popis: L(+)-Arginin 98+%

Bezpečnostní list

Katalogové číslo: (USBIT2040-06F)

Dodavatel: US Biological

Popis: Anti-TCR, gamma, delta Hamster Monoclonal Antibody [clone: 5K24]

Měrná jednotka: 1 * 500 µG

Akce

Katalogové číslo: (ABCAAB32401-100)

Dodavatel: Abcam

Popis: Anti-PI 3 Kinase p110 delta Rabbit Monoclonal Antibody [clone: Y387]

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-3727R)

Dodavatel: Bioss

Popis: Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Thermo Fisher Scientific

Popis: (R)-4-Hydroxypyrrolidin-2-one 97%

Bezpečnostní list

Katalogové číslo: (USBI0014-24B-FITC)

Dodavatel: US Biological

Popis: Anti-14-3-3 delta/zeta Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI0014-24A-FITC)

Dodavatel: US Biological

Popis: Anti-14-3-3 delta/zeta Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Měrná jednotka: 1 * 200 µl

Akce

Katalogové číslo: (USBI0014-24A-HRP)

Dodavatel: US Biological

Popis: Anti-14-3-3 delta/zeta Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce

Dodavatel: Apollo Scientific

Popis: Material may contain up to 25% polymerised material which can be reverted to the product by distillation.

Katalogové číslo: (BOSSBS-12391R-A647)

Dodavatel: Bioss

Popis: MIB1 is a 1006 amino acid E3 ubiquitin ligase that activates the Notch ligand, Delta. MIB1 ubiquinates Delta by binding to its intracellular domain, leading to the endocytosis and eventual degradation of the Delta receptor, which, paradoxically, results in the up-regulation of receptor activity and enhances Notch signaling. MIB1 also interacts with DAPK, a protein that plays an important role in the regulation of apoptosis. Ubiquination of DAPK leads to inhibition of caspase-dependent apoptosis, therefore it is likely that overexpression of MIB1 can lead to tumor growth. Although it seems to be widely expressed at low levels, MIB1 is expressed at highest concentrations in the CNS and ovary. Both DAPK and MIB1 are overexpressed in epileptic brain tissue, suggesting that they probably cooperate as regulators of neuronal death in epilepsy.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-12391R-CY3)

Dodavatel: Bioss

Popis: MIB1 is a 1006 amino acid E3 ubiquitin ligase that activates the Notch ligand, Delta. MIB1 ubiquinates Delta by binding to its intracellular domain, leading to the endocytosis and eventual degradation of the Delta receptor, which, paradoxically, results in the up-regulation of receptor activity and enhances Notch signaling. MIB1 also interacts with DAPK, a protein that plays an important role in the regulation of apoptosis. Ubiquination of DAPK leads to inhibition of caspase-dependent apoptosis, therefore it is likely that overexpression of MIB1 can lead to tumor growth. Although it seems to be widely expressed at low levels, MIB1 is expressed at highest concentrations in the CNS and ovary. Both DAPK and MIB1 are overexpressed in epileptic brain tissue, suggesting that they probably cooperate as regulators of neuronal death in epilepsy.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (USBI042370-HRP)

Dodavatel: US Biological

Popis: Anti-Staphylococcus aureus, delta Hemolysin Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Měrná jednotka: 1 * 200 µl

Akce